Names & Taxonomy
- Uniprot ID:
- O60774
- Entry Name:
- FMO6_HUMAN
- Status:
- reviewed
- Protein Names:
- Putative dimethylaniline monooxygenase [N-oxide-forming] 6 (EC 1.14.13.8) (Dimethylaniline oxidase 6) (Flavin-containing monooxygenase 6) (FMO 6)
- Gene Names:
- FMO6P FMO6
- Gene Names Primary:
- FMO6P
- Organism:
- Homo sapiens (Human)
Structure
- Length:
- 539
- Sequence:
- MSKRVGIIGAGVSGLAAIWCCLEEGLEPTCFERSDDVGGLWKFSDHTEEGRASIYQSVFTNSSKEMMCFPDFPYPDDYPNYIHHSKLQEYIKTYAQKKDLLRYIQFETLVSGIKKCPSFLVTGQWVVVTEKDGKQESTIFDAVMICSGHHVYPNLPTDSFPGLDQFRGNYLHSRDYKNPEAFKGKRVLVIGLGNSGSDIAVELSRLATQVIISTRSASWVMSRVWDDGYPWDMMYVTRFASFLRNVLPSFISDWLYVQKMNTWFKHENYGLMPLNGSLRKEPVFNDELPSRILCGTLSIKPSVKEFTETSAVFEDGTMFEAIDSVIFATGYDYSYPFLDETIMKSRNNEVTLFKGIFPPLMEKPTLAVIGLVQSLGAAIPTADLQAWWAAKVFANSCTLPTTNEMMDDTDEKMGKKLKCMFSSFFMFGQSQTLQTDYITYVDELGSFIGAKPNIPWLFLTDPRLALEVYFGPCSPYQFRLMGPGKWDGARNAILTQWNRTVKPTRTRVVSEVQRPHPFYNLLKMLSFPLLLLAVTLTFY
- Proteomes:
- UP000005640
Subcellular location
- Subcellular Location:
- Microsome membrane
Function
- Function:
- It is probable that this protein is only produced in very small quantity or not at all as the gene coding for it seems to be unable to produce full length transcripts.
- Catalytic Activity:
- N,N-dimethylaniline + NADPH + O(2) = N,N-dimethylaniline N-oxide + NADP(+) + H(2)O.
- Cofactor:
- COFACTOR: Name=FAD; Xref=ChEBI:CHEBI:57692;
- Gene Ontology Go:
- endoplasmic reticulum membrane
integral component of membrane
flavin adenine dinucleotide binding
monooxygenase activity
N,N-dimethylaniline monooxygenase activity
NADP binding
oxidation-reduction process - Gene Ontology Biological Process:
- oxidation-reduction process
- Gene Ontology Molecular Function:
- flavin adenine dinucleotide binding
monooxygenase activity
N,N-dimethylaniline monooxygenase activity
NADP binding - Gene Ontology Cellular Component:
- endoplasmic reticulum membrane
integral component of membrane - Keywords:
- Complete proteome
Endoplasmic reticulum
FAD
Flavoprotein
Membrane
Microsome
Monooxygenase
NADP
Oxidoreductase
Polymorphism
Reference proteome
Transmembrane
Transmembrane helix