Names & Taxonomy
- Uniprot ID:
- O43772
- Entry Name:
- MCAT_HUMAN
- Status:
- reviewed
- Protein Names:
- Mitochondrial carnitine/acylcarnitine carrier protein (Carnitine/acylcarnitine translocase) (CAC) (Solute carrier family 25 member 20)
- Gene Names:
- SLC25A20 CAC CACT
- Gene Names Primary:
- SLC25A20
- Organism:
- Homo sapiens (Human)
Structure
- Length:
- 301
- Sequence:
- MADQPKPISPLKNLLAGGFGGVCLVFVGHPLDTVKVRLQTQPPSLPGQPPMYSGTFDCFRKTLFREGITGLYRGMAAPIIGVTPMFAVCFFGFGLGKKLQQKHPEDVLSYPQLFAAGMLSGVFTTGIMTPGERIKCLLQIQASSGESKYTGTLDCAKKLYQEFGIRGIYKGTVLTLMRDVPASGMYFMTYEWLKNIFTPEGKRVSELSAPRILVAGGIAGIFNWAVAIPPDVLKSRFQTAPPGKYPNGFRDVLRELIRDEGVTSLYKGFNAVMIRAFPANAACFLGFEVAMKFLNWATPNL
- Proteomes:
- UP000005640
Subcellular location
- Subcellular Location:
- Mitochondrion inner membrane; Multi-pass membrane protein.
Function
- Function:
- Mediates the transport of acylcarnitines of different length across the mitochondrial inner membrane from the cytosol to the mitochondrial matrix for their oxidation by the mitochondrial fatty acid-oxidation pathway.
- Cross Reference Drug Bank:
- DB00583
- Gene Ontology Go:
- cytoplasm
integral component of membrane
mitochondrial inner membrane
mitochondrion
structural constituent of ribosome
carnitine shuttle
cellular lipid metabolic process
small molecule metabolic process
translation - Gene Ontology Biological Process:
- carnitine shuttle
cellular lipid metabolic process
small molecule metabolic process
translation - Gene Ontology Molecular Function:
- structural constituent of ribosome
- Gene Ontology Cellular Component:
- cytoplasm
integral component of membrane
mitochondrial inner membrane
mitochondrion - Keywords:
- Acetylation
Complete proteome
Disease mutation
Membrane
Mitochondrion
Mitochondrion inner membrane
Reference proteome
Repeat
Transmembrane
Transmembrane helix
Transport