Names & Taxonomy
- Uniprot ID:
- H9E7F7
- Entry Name:
- H9E7F7_HUMAN
- Status:
- unreviewed
- Protein Names:
- Cytochrome c oxidase subunit 2 (Fragment)
- Gene Names:
- COX2
- Gene Names Primary:
- COX2
- Organism:
- Homo sapiens (Human)
Structure
- Length:
- 217
- Sequence:
- DATSPIMEELITFHDHALMIIFLICFLVLYALFLTLTTKLTNTNISDAQEMETVWTILPAIILVLIALPSLRILYMTDEVNDPSLTIKSIGHQWYWTYEYTDYGGLIFNSYMLPPLFLEPGDLRLLDVDNRVVLPIEAPIRMMITSQDVLHSWAVPTLGLKTDAIPGRLNQTTFTATRPGVYYGQCSEICGANHSFMPIVLELIPLKIFEMGPVFTL
Subcellular location
- Subcellular Location:
- Mitochondrion inner membrane
- Gene Encoded:
- Mitochondrion
Function
- Function:
- Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1-3 form the functional core of the enzyme complex. Subunit 2 transfers the electrons from cytochrome c via its binuclear copper A center to the bimetallic center of the catalytic subunit 1.
- Cofactor:
- COFACTOR: Name=Cu cation; Xref=ChEBI:CHEBI:23378;
- Gene Ontology Go:
- integral component of membrane
mitochondrial inner membrane
respiratory chain
copper ion binding
cytochrome-c oxidase activity
electron transport chain - Gene Ontology Biological Process:
- electron transport chain
- Gene Ontology Molecular Function:
- copper ion binding
cytochrome-c oxidase activity - Gene Ontology Cellular Component:
- integral component of membrane
mitochondrial inner membrane
respiratory chain - Keywords:
- Copper
Electron transport
Membrane
Metal-binding
Mitochondrion
Mitochondrion inner membrane
Respiratory chain
Transmembrane
Transmembrane helix
Transport
Publication
- PubMed ID:
- 22427842