Names & Taxonomy
- Uniprot ID:
- H7C4I3
- Entry Name:
- H7C4I3_HUMAN
- Status:
- unreviewed
- Protein Names:
- RuvB-like helicase (EC 3.6.4.12) (Fragment)
- Gene Names:
- RUVBL1
- Gene Names Primary:
- RUVBL1
- Organism:
- Homo sapiens (Human)
Structure
- Length:
- 222
- Sequence:
- XKERVEAGDVIYIEANSGAVKRQGRCDTYATEFDLEAEEYVPLPKGDVHKKKEIIQDVTLHDLDVANARPQGGQDILSMMGQLMKPKKTEITDKLRGEINKVVNKYIDQGIAELVPGVLFVDEVHMLDIECFTYLHRALESSIAPIVIFASNRGNCVIRSHDSMNMLVQLIWKPAAFKYHLIVSTQYDDSAPHRVGDCTQGILKLKSRPWKLPGVGSGHTWK
- Proteomes:
- UP000005640
Subcellular location
- Subcellular Location:
- Nucleus
Function
- Function:
- Proposed core component of the chromatin remodeling INO80 complex which is involved in transcriptional regulation, DNA replication and probably DNA repair.
- Catalytic Activity:
- ATP + H(2)O = ADP + phosphate.
- Gene Ontology Go:
- nucleus
ATP binding
ATP-dependent 5'-3' DNA helicase activity
DNA recombination
DNA repair
regulation of transcription, DNA-templated
transcription, DNA-templated - Gene Ontology Biological Process:
- DNA recombination
DNA repair
regulation of transcription, DNA-templated
transcription, DNA-templated - Gene Ontology Molecular Function:
- ATP binding
ATP-dependent 5'-3' DNA helicase activity - Gene Ontology Cellular Component:
- nucleus
- Keywords:
- ATP-binding
Complete proteome
DNA damage
DNA recombination
DNA repair
Helicase
Hydrolase
Nucleotide-binding
Nucleus
Proteomics identification
Reference proteome
Transcription
Transcription regulation