Names & Taxonomy
- Uniprot ID:
- E9PCM2
- Entry Name:
- E9PCM2_HUMAN
- Status:
- unreviewed
- Protein Names:
- Prestin (Solute carrier family 26 member 5)
- Gene Names:
- SLC26A5
- Gene Names Primary:
- SLC26A5
- Organism:
- Homo sapiens (Human)
Structure
- Length:
- 707
- Sequence:
- MDHAEENEILAATQRYYVERPIFSHPVLQERLHTKDKVPDSIADKLKQAFTCTPKKIRNIIYMFLPITKWLPAYKFKEYVLGDLVSGISTGVLQLPQGPFAVISLMIGGVAVRLVPDDIVIPGGVNATNGTEARDALRVKVAMSVTLLSGIIQFCLGVCRFGFVAIYLTEPLVRGFTTAAAVHVFTSMLKYLFGVKTKRYSGIFSVVYSTVAVLQNVKNLNVCSLGVGLMVFGLLLGGKEFNERFKEKLPAPIPLEFFAVVMGTGISAGFNLKESYNVDVVGTLPLGLLPPANPDTSLFHLVYVDAIAIAIVGFSVTISMAKTLANKHGYQVDGNQELIALGLCNSIGSLFQTFSISCSLSRSLVQEGTGGKTQLAGCLASLMILLVILATGFLFESLPQAVLSAIVIVNLKGMFMQFSDLPFFWRTSKIELTIWLTTFVSSLFLGLDYGLITAVIIALLTVIYRTQSPSYKVLGKLPETDVYIDIDAYEEVKEIPGIKIFQINAPIYYANSDLYSNALKRKTGVNPAVIMGARRKAMRKYAKEVGNANMANATVVKADAEVDGEDATKPEEEDGEVKYPPIVIKSTFPEEMQRFMPPGDNVHTVILDFTQVNFIDSVGVKTLAGIVKEYGDVGIYVYLAGCSAQVVNDLTRNRFFENPALWELLFHSIHDAVLGSQLREALAEQEASAPPSQEDLEPNATPATPEA
- Proteomes:
- UP000005640
Subcellular location
- Subcellular Location:
- Membrane
Function
- Function:
- Motor protein that converts auditory stimuli to length changes in outer hair cells and mediates sound amplification in the mammalian hearing organ.
- Gene Ontology Go:
- integral component of membrane
secondary active sulfate transmembrane transporter activity
regulation of cell shape
sensory perception of sound - Gene Ontology Biological Process:
- regulation of cell shape
sensory perception of sound - Gene Ontology Molecular Function:
- secondary active sulfate transmembrane transporter activity
- Gene Ontology Cellular Component:
- integral component of membrane
- Keywords:
- Cell shape
Complete proteome
Hearing
Membrane
Motor protein
Reference proteome
Transmembrane
Transmembrane helix
Publication
- PubMed ID:
- 12853948