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Uniprot ID:: A0A024RC70
Entry Name:: A0A024RC70_HUMAN
Status:: unreviewed
Protein Names:: Furin (Paired basic amino acid cleaving enzyme), isoform CRA_a
Gene Names:: FURIN hCG_32577
Gene Names Orf:: hCG_32577
Gene Names Primary:: FURIN
Organism:: Homo sapiens (Human)

Length:: 794
Sequence:: MELRPWLLWVVAATGTLVLLAADAQGQKVFTNTWAVRIPGGPAVANSVARKHGFLNLGQIFGDYYHFWHRGVTKRSLSPHRPRHSRLQREPQVQWLEQQVAKRRTKRDVYQEPTDPKFPQQWYLSGVTQRDLNVKAAWAQGYTGHGIVVSILDDGIEKNHPDLAGNYDPGASFDVNDQDPDPQPRYTQMNDNRHGTRCAGEVAAVANNGVCGVGVAYNARIGGVRMLDGEVTDAVEARSLGLNPNHIHIYSASWGPEDDGKTVDGPARLAEEAFFRGVSQGRGGLGSIFVWASGNGGREHDSCNCDGYTNSIYTLSISSATQFGNVPWYSEACSSTLATTYSSGNQNEKQIVTTDLRQKCTESHTGTSASAPLAAGIIALTLEANKNLTWRDMQHLVVQTSKPAHLNANDWATNGVGRKVSHSYGYGLLDAGAMVALAQNWTTVAPQRKCIIDILTEPKDIGKRLEVRKTVTACLGEPNHITRLEHAQARLTLSYNRRGDLAIHLVSPMGTRSTLLAARPHDYSADGFNDWAFMTTHSWDEDPSGEWVLEIENTSEANNYGTLTKFTLVLYGTAPEGLPVPPESSGCKTLTSSQACVVCEEGFSLHQKSCVQHCPPGFAPQVLDTHYSTENDVETIRASVCAPCHASCATCQGPALTDCLSCPSHASLDPVEQTCSRQSQSSRESPPQQQPPRLPPEVEAGQRLRAGLLPSHLPEVVAGLSCAFIVLVFVTVFLVLQLRSGFSFRGVKVYTMDRGLISYKGLPPEAWQEECPSDSEEDEGRGERTAFIKDQSAL

Gene Ontology Go:: endoplasmic reticulum membrane
Golgi cisterna
integral component of membrane
plasma membrane
serine-type endopeptidase activity
aging
positive regulation of cell migration
positive regulation of transforming growth factor beta receptor signaling pathway
protein processing
regulation of low-density lipoprotein particle receptor biosynthetic process
Gene Ontology Biological Process:: aging
positive regulation of cell migration
positive regulation of transforming growth factor beta receptor signaling pathway
protein processing
regulation of low-density lipoprotein particle receptor biosynthetic process
Gene Ontology Molecular Function:: serine-type endopeptidase activity
Gene Ontology Cellular Component:: endoplasmic reticulum membrane
Golgi cisterna
integral component of membrane
plasma membrane
Keywords:: Hydrolase
Membrane
Protease
Serine protease
Signal
Transmembrane
Transmembrane helix