Names & Taxonomy
- Uniprot ID:
- A0A024RBC7
- Entry Name:
- A0A024RBC7_HUMAN
- Status:
- unreviewed
- Protein Names:
- Calcium-transporting ATPase (EC 3.6.3.8)
- Gene Names:
- ATP2B1 hCG_27605
- Gene Names Orf:
- hCG_27605
- Gene Names Primary:
- ATP2B1
- Organism:
- Homo sapiens (Human)
Structure
- Length:
- 1220
- Sequence:
- MGDMANNSVAYSGVKNSLKEANHDGDFGITLAELRALMELRSTDALRKIQESYGDVYGICTKLKTSPNEGLSGNPADLERREAVFGKNFIPPKKPKTFLQLVWEALQDVTLIILEIAAIVSLGLSFYQPPEGDNALCGEVSVGEEEGEGETGWIEGAAILLSVVCVVLVTAFNDWSKEKQFRGLQSRIEQEQKFTVIRGGQVIQIPVADITVGDIAQVKYGDLLPADGILIQGNDLKIDESSLTGESDHVKKSLDKDPLLLSGTHVMEGSGRMVVTAVGVNSQTGIIFTLLGAGGEEEEKKDEKKKEKKNKKQDGAIENRNKAKAQDGAAMEMQPLKSEEGGDGDEKDKKKANLPKKEKSVLQGKLTKLAVQIGKAGLLMSAITVIILVLYFVIDTFWVQKRPWLAECTPIYIQYFVKFFIIGVTVLVVAVPEGLPLAVTISLAYSVKKMMKDNNLVRHLDACETMGNATAICSDKTGTLTMNRMTVVQAYINEKHYKKVPEPEAIPPNILSYLVTGISVNCAYTSKILPPEKEGGLPRHVGNKTECALLGLLLDLKRDYQDVRNEIPEEALYKVYTFNSVRKSMSTVLKNSDGSYRIFSKGASEIILKKCFKILSANGEAKVFRPRDRDDIVKTVIEPMASEGLRTICLAFRDFPAGEPEPEWDNENDIVTGLTCIAVVGIEDPVRPEVPDAIKKCQRAGITVRMVTGDNINTARAIATKCGILHPGEDFLCLEGKDFNRRIRNEKGEIEQERIDKIWPKLRVLARSSPTDKHTLVKGIIDSTVSDQRQVVAVTGDGTNDGPALKKADVGFAMGIAGTDVAKEASDIILTDDNFTSIVKAVMWGRNVYDSISKFLQFQLTVNVVAVIVAFTGACITQDSPLKAVQMLWVNLIMDTLASLALATEPPTESLLLRKPYGRNKPLISRTMMKNILGHAFYQLVVVFTLLFAGEKFFDIDSGRNAPLHAPPSEHYTIVFNTFVLMQLFNEINARKIHGERNVFEGIFNNAIFCTIVLGTFVVQIIIVQFGGKPFSCSELSIEQWLWSIFLGMGTLLWGQLISTIPTSRLKFLKEAGHGTQKEEIPEEELAEDVEEIDHAERELRRGQILWFRGLNRIQTQIRVVNAFRSSLYEGLEKPESRSSIHNFMTHPEFRIEDSEPHIPLIDDTDAEDDAPTKRNSSPPPSPNKNNNAVDSGIHLTIEMNKSATSSSPGSPLHSLETSL
Subcellular location
- Subcellular Location:
- Membrane
Function
- Function:
- This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium.
- Catalytic Activity:
- ATP + H(2)O + Ca(2+)(Side 1) = ADP + phosphate + Ca(2+)(Side 2).
- Gene Ontology Go:
- apical plasma membrane
basolateral plasma membrane
cytoplasmic side of plasma membrane
dendritic spine membrane
integral component of membrane
membrane raft
neuronal cell body membrane
nucleus
plasma membrane
ATP binding
calcium-transporting ATPase activity
metal ion binding
aging
brain development
calcium ion export
cellular response to corticosterone stimulus
cellular response to vitamin D
neural retina development
response to cold - Gene Ontology Biological Process:
- aging
brain development
calcium ion export
cellular response to corticosterone stimulus
cellular response to vitamin D
neural retina development
response to cold - Gene Ontology Molecular Function:
- ATP binding
calcium-transporting ATPase activity
metal ion binding - Gene Ontology Cellular Component:
- apical plasma membrane
basolateral plasma membrane
cytoplasmic side of plasma membrane
dendritic spine membrane
integral component of membrane
membrane raft
neuronal cell body membrane
nucleus
plasma membrane - Keywords:
- ATP-binding
Calcium
Calcium transport
Hydrolase
Ion transport
Membrane
Nucleotide-binding
Transmembrane
Transmembrane helix
Transport
Publication
- PubMed ID:
- 11181995