Names & Taxonomy
- Uniprot ID:
- A0A024R6H1
- Entry Name:
- A0A024R6H1_HUMAN
- Status:
- unreviewed
- Protein Names:
- Serine palmitoyltransferase, long chain base subunit 2, isoform CRA_a
- Gene Names:
- SPTLC2 hCG_22264
- Gene Names Orf:
- hCG_22264
- Gene Names Primary:
- SPTLC2
- Organism:
- Homo sapiens (Human)
Structure
- Length:
- 562
- Sequence:
- MRPEPGGCCCRRTVRANGCVANGEVRNGYVRSSAAAAAAAAAGQIHHVTQNGGLYKRPFNEAFEETPMLVAVLTYVGYGVLTLFGYLRDFLRYWRIEKCHHATEREEQKDFVSLYQDFENFYTRNLYMRIRDNWNRPICSVPGARVDIMERQSHDYNWSFKYTGNIIKGVINMGSYNYLGFARNTGSCQEAAAKVLEEYGAGVCSTRQEIGNLDKHEELEELVARFLGVEAAMAYGMGFATNSMNIPALVGKGCLILSDELNHASLVLGARLSGATIRIFKHNNMQSLEKLLKDAIVYGQPRTRRPWKKILILVEGIYSMEGSIVRLPEVIALKKKYKAYLYLDEAHSIGALGPTGRGVVEYFGLDPEDVDVMMGTFTKSFGASGGYIGGKKELIDYLRTHSHSAVYATSLSPPVVEQIITSMKCIMGQDGTSLGKECVQQLAENTRYFRRRLKEMGFIIYGNEDSPVVPLMLYMPAKIGAFGREMLKRNIGVVVVGFPATPIIESRARFCLSAAHTKEILDTALKEIDEVGDLLQLKYSRHRLVPLLDRPFDETTYEETED
Function
- Cofactor:
- COFACTOR: Name=pyridoxal 5'-phosphate; Xref=ChEBI:CHEBI:597326;
- Gene Ontology Go:
- mitochondrion
pyridoxal phosphate binding
serine C-palmitoyltransferase activity
ceramide biosynthetic process
sphinganine biosynthetic process
sphingomyelin biosynthetic process
sphingosine biosynthetic process - Gene Ontology Biological Process:
- ceramide biosynthetic process
sphinganine biosynthetic process
sphingomyelin biosynthetic process
sphingosine biosynthetic process - Gene Ontology Molecular Function:
- pyridoxal phosphate binding
serine C-palmitoyltransferase activity - Gene Ontology Cellular Component:
- mitochondrion
- Keywords:
- Pyridoxal phosphate
Transferase
Publication
- PubMed ID:
- 11181995