Names & Taxonomy

Uniprot ID:
A8K9L3
Entry Name:
A8K9L3_HUMAN
Status:
unreviewed
Protein Names:
Proteolipid protein 1 (Pelizaeus-Merzbacher disease, spastic paraplegia 2, uncomplicated), isoform CRA_b (Proteolipid protein 1 isoform 2) (cDNA FLJ77822, highly similar to Homo sapiens proteolipid protein 1 (Pelizaeus-Merzbacher disease,spastic paraplegia 2, uncomplicated) (PLP1), mRNA) (cDNA, FLJ92659, highly similar to Homo sapiens proteolipid protein 1 (Pelizaeus-Merzbacher disease,spastic paraplegia 2, uncomplicated) (PLP1), mRNA)
Gene Names:
PLP1 hCG_17970
Gene Names Orf:
hCG_17970
Gene Names Primary:
PLP1
Organism:
Homo sapiens (Human)

Structure

Length:
277
Sequence:
MGLLECCARCLVGAPFASLVATGLCFFGVALFCGCGHEALTGTEKLIETYFSKNYQDYEYLINVIHAFQYVIYGTASFFFLYGALLLAEGFYTTGAVRQIFGDYKTTICGKGLSATVTGGQKGRGSRGQHQAHSLERVCHCLGKWLGHPDKFVGITYALTVVWLLVFACSAVPVYIYFNTWTTCQSIAFPSKTSASIGSLCADARMYGVLPWNAFPGKVCGSNLLSICKTAEFQMTFHLFIAAFVGAAATLVSLLTFMIAATYNFAVLKLMGRGTKF

Function

Gene Ontology Go:
integral component of membrane
myelin sheath
structural constituent of myelin sheath
astrocyte development
axon development
cell maturation
central nervous system myelination
inflammatory response
integrin-mediated signaling pathway
long-chain fatty acid biosynthetic process
positive regulation of gene expression
Gene Ontology Biological Process:
astrocyte development
axon development
cell maturation
central nervous system myelination
inflammatory response
integrin-mediated signaling pathway
long-chain fatty acid biosynthetic process
positive regulation of gene expression
Gene Ontology Molecular Function:
structural constituent of myelin sheath
Gene Ontology Cellular Component:
integral component of membrane
myelin sheath
Keywords:
Membrane
Transmembrane
Transmembrane helix

Publication

PubMed ID:
11181995