Names & Taxonomy
- Uniprot ID:
- A8K6T3
- Entry Name:
- A8K6T3_HUMAN
- Status:
- unreviewed
- Protein Names:
- cDNA FLJ78674, highly similar to Homo sapiens desmocollin type 4
- Organism:
- Homo sapiens (Human)
Structure
- Length:
- 896
- Sequence:
- MAAAGPRRSVRGAVCLHLLLTLVIFSRAGEACKKVILNVPSKLEADKIIGRVNLEECFRSADLIRSSDPDFRVLNDGTVYTARAVALSDKKRSFTIWLSDKKKQTQKEVTVLLEHQKKVSKTRHTRETVLRRAKRRWAPIPCSMQENSLGPFPLFLQQVESDAAQNYTVFYSISGRGVDKEPLNLFYIERDTGNLFCTRPVDREEYDVFDLIAYASTADGYSADLPHPLPIRVEDENDNHPVFTEAIYNFEVLESSRPGTTVGVVCATDRDEPDTMHTRLKYSILQQTPRSPGLFSVHPSTGVITTVSHYLDREVVDKYSLIMKVQDMDGQFFGLIGTSTCIITVTDSNDNAPTFRQNAYEAFVEENAFNVEILRIPIEDKDLINTANWRVNFTILKGNENGHFKISTDKETNEGVLSVVKPLNYEENRQVNLEIGVNNEAPFARDIPRVTALNRALVTVHVRDLDEGPECTPAAQYVRIKENLAVGSKINGYKAYDPENRNGNGLRYKKLHDPKGWITIDEISGSIITSKILDREVETPKNELYNITVLAIDKDDRSCTGTLAVNIEDVNDNPPEILQEYVVICKPKMGYTDILAVDPDEPVHGAPFYFSLPNTSPEISRLWSLTKVNDTAARLSYQKNAGFQEYTIPITVKDRAGQAATKLLRVNLCECTHPTQCRATSRSTGVILGKWAILAILLGIALLFSVLLTLVCGVFGATKGKRFPEDLAQQNLIISNTEAPGDDRVCSANGFMTQTTNNSSQGFCGTMGSGMKNGGQETIEMMKGGNQTLESCRGAGHHHTLDSCRGGHTEVDNCRYTYSEWHSFTQPRLGEKLHRCNQNEDRMPSQDYVLTYNYEGRGSPAGSVGCCSEKQEEDGLDFLNNLEPKFITLAEACTKR
Subcellular location
- Subcellular Location:
- Cell membrane
Function
- Function:
- Component of intercellular desmosome junctions. Involved in the interaction of plaque proteins and intermediate filaments mediating cell-cell adhesion.
- Gene Ontology Go:
- integral component of membrane
plasma membrane
calcium ion binding
homophilic cell adhesion via plasma membrane adhesion molecules - Gene Ontology Biological Process:
- homophilic cell adhesion via plasma membrane adhesion molecules
- Gene Ontology Molecular Function:
- calcium ion binding
- Gene Ontology Cellular Component:
- integral component of membrane
plasma membrane - Keywords:
- Calcium
Cell adhesion
Cell membrane
Membrane
Repeat
Signal
Transmembrane
Transmembrane helix