Names & Taxonomy
- Uniprot ID:
- A8K2N0
- Entry Name:
- A8K2N0_HUMAN
- Status:
- unreviewed
- Protein Names:
- cDNA FLJ77835, highly similar to Homo sapiens complement component 1, s subcomponent (C1S), transcript variant 2, mRNA
- Organism:
- Homo sapiens (Human)
Structure
- Length:
- 688
- Sequence:
- MWCIVLFSLLAWVYAEPTMYGEILSPNYPQAYPSEVEKSWDIEVPEGYGIHLYFTHLDIELSENCAYDSVQIISGDTEEGRLCGQRSSNNPHSPIVEEFQVPYNKLQVIFKSDFSNEERFTGFAAYYVATDINECTDFVDVPCSHFCNNFIGGYFCSCPPEYFLHDDMKNCGVNCSGDVFTALIGEIASPNYPKPYPENSRCEYQIRLEKGFQVVVTLRREDFDVEAADSAGNCLDSLVFVAGDRQFGPYCGHGFPGPLNIETKSNALDIIFQTDLTGQKKGWKLRYHGDPMPCPKEDTPNSVWEPAKAKYVFRDVVQITCLDGFEVVEGRVGATSFYSTCQSNGKWSNSKLKCQPVDCGIPESIENGKVEDPESTLFGSVIRYTCEEPYYYMENGGGGEYHCAGNGSWVNEVLGPELPKCVPVCGVPREPFEEKQRIIGGSDADIKNFPWQVFFDNPWAGGALINEYWVLTAAHVVEGNREPTMYVGSTSVQTSRLAKSKMLTPEHVFIHPGWKLLEVPEGRTNFDNDIALVRLKDPVKMGPTVSPICLPGTSSDYNLMDGDLGLISGWGRTEKRDRAVRLKAARLPVAPLRKCKEVKVGKPTADAEAYVFTPNMICAGGEKGMDSCKGDSGGAFAVQDPNDKTKFYAAGLVSWGPQCGTYGLYTRVKNYVDWIMKTMQENSTPRED
Function
- Active Site:
- ACT_SITE 475 475 Charge relay system.
- Gene Ontology Go:
- extracellular region
calcium ion binding
serine-type endopeptidase activity
complement activation - Gene Ontology Biological Process:
- complement activation
- Gene Ontology Molecular Function:
- calcium ion binding
serine-type endopeptidase activity - Gene Ontology Cellular Component:
- extracellular region
- Keywords:
- Calcium
Disulfide bond
EGF-like domain
Hydrolase
Hydroxylation
Metal-binding
Protease
Repeat