Names & Taxonomy
- Uniprot ID:
- V9HVZ4
- Entry Name:
- V9HVZ4_HUMAN
- Status:
- unreviewed
- Protein Names:
- Glyceraldehyde-3-phosphate dehydrogenase (EC 1.2.1.12)
- Gene Names:
- HEL-S-162eP
- Gene Names Primary:
- HEL-S-162eP
- Organism:
- Homo sapiens (Human)
Structure
- Length:
- 335
- Sequence:
- MGKVKVGVNGFGRIGRLVTRAAFNSGKVDIVAINDPFIDLNYMVYMFQYDSTHGKFHGTVKAENGKLVINGNPITIFQERDPSKIKWGDAGAEYVVESTGVFTTMEKAGAHLQGGAKRVIISAPSADAPMFVMGVNHEKYDNSLKIISNASCTTNCLAPLAKVIHDNFGIVEGLMTTVHAITATQKTVDGPSGKLWRDGRGALQNIIPASTGAAKAVGKVIPELNGKLTGMAFRVPTANVSVVDLTCRLEKPAKYDDIKKVVKQASEGPLKGILGYTEHQVVSSDFNSDTHSSTFDAGAGIALNDHFVKLISWYDNEFGYSNRVVDLMAHMASKE
Function
- Pathway:
- Carbohydrate degradation; glycolysis; pyruvate from D-glyceraldehyde 3-phosphate: step 1/5.
- Catalytic Activity:
- D-glyceraldehyde 3-phosphate + phosphate + NAD(+) = 3-phospho-D-glyceroyl phosphate + NADH.
- Active Site:
- ACT_SITE 152 152 Nucleophile.
- Gene Ontology Go:
- cytoplasm
intracellular membrane-bounded organelle
nuclear membrane
plasma membrane
glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
NAD binding
NADP binding
glucose metabolic process
glycolytic process - Gene Ontology Biological Process:
- glucose metabolic process
glycolytic process - Gene Ontology Molecular Function:
- glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
NAD binding
NADP binding - Gene Ontology Cellular Component:
- cytoplasm
intracellular membrane-bounded organelle
nuclear membrane
plasma membrane - Keywords:
- Glycolysis
NAD
Oxidoreductase