Names & Taxonomy

Uniprot ID:
A0A024R2Z8
Entry Name:
A0A024R2Z8_HUMAN
Status:
unreviewed
Protein Names:
Parathyroid hormone receptor 1, isoform CRA_a
Gene Names:
PTHR1 hCG_14653
Gene Names Orf:
hCG_14653
Gene Names Primary:
PTHR1
Organism:
Homo sapiens (Human)

Structure

Length:
593
Sequence:
MGTARIAPGLALLLCCPVLSSAYALVDADDVMTKEEQIFLLHRAQAQCEKRLKEVLQRPASIMESDKGWTSASTSGKPRKDKASGKLYPESEEDKEAPTGSRYRGRPCLPEWDHILCWPLGAPGEVVAVPCPDYIYDFNHKGHAYRRCDRNGSWELVPGHNRTWANYSECVKFLTNETREREVFDRLGMIYTVGYSVSLASLTVAVLILAYFRRLHCTRNYIHMHLFLSFMLRAVSIFVKDAVLYSGATLDEAERLTEEELRAIAQAPPPPATAAAGYAGCRVAVTFFLYFLATNYYWILVEGLYLHSLIFMAFFSEKKYLWGFTVFGWGLPAVFVAVWVSVRATLANTGCWDLSSGNKKWIIQVPILASIVLNFILFINIVRVLATKLRETNAGRCDTRQQYRKLLKSTLVLMPLFGVHYIVFMATPYTEVSGTLWQVQMHYEMLFNSFQGFFVAIIYCFCNGEVQAEIKKSWSRWTLALDFKRKARSGSSSYSYGPMVSHTSVTNVGPRVGLGLPLSPRLLPTATTNGHPQLPGHAKPGTPALETLETTPPAMAAPKDDGFLNGSCSGLDEEASGPERPPALLQEEWETVM

Function

Gene Ontology Go:
apical plasma membrane
basolateral plasma membrane
brush border membrane
cytosol
integral component of membrane
nucleus
receptor complex
parathyroid hormone receptor activity
peptide hormone binding
adenylate cyclase-activating G-protein coupled receptor signaling pathway
aging
bone mineralization
bone resorption
cell maturation
cell surface receptor signaling pathway
chondrocyte differentiation
negative regulation of cell proliferation
osteoblast development
phospholipase C-activating G-protein coupled receptor signaling pathway
positive regulation of cell proliferation
positive regulation of cytosolic calcium ion concentration
positive regulation of inositol phosphate biosynthetic process
Gene Ontology Biological Process:
adenylate cyclase-activating G-protein coupled receptor signaling pathway
aging
bone mineralization
bone resorption
cell maturation
cell surface receptor signaling pathway
chondrocyte differentiation
negative regulation of cell proliferation
osteoblast development
phospholipase C-activating G-protein coupled receptor signaling pathway
positive regulation of cell proliferation
positive regulation of cytosolic calcium ion concentration
positive regulation of inositol phosphate biosynthetic process
Gene Ontology Molecular Function:
parathyroid hormone receptor activity
peptide hormone binding
Gene Ontology Cellular Component:
apical plasma membrane
basolateral plasma membrane
brush border membrane
cytosol
integral component of membrane
nucleus
receptor complex
Keywords:
G-protein coupled receptor
Membrane
Receptor
Signal
Transducer
Transmembrane
Transmembrane helix

Publication

PubMed ID:
11181995