Names & Taxonomy

Uniprot ID:
A6BM72
Entry Name:
MEG11_HUMAN
Status:
reviewed
Protein Names:
Multiple epidermal growth factor-like domains protein 11 (Multiple EGF-like domains protein 11)
Gene Names:
MEGF11 KIAA1781 UNQ1949/PRO4432
Gene Names Orf:
UNQ1949/PRO4432
Gene Names Primary:
MEGF11
Organism:
Homo sapiens (Human)

Structure

Length:
1044
Sequence:
MVLSLTGLIAFSFLQATLALNPEDPNVCSHWESYAVTVQESYAHPFDQIYYTRCTDILNWFKCTRHRISYKTAYRRGLRTMYRRRSQCCPGYYESGDFCIPLCTEECVHGRCVSPDTCHCEPGWGGPDCSSGCDSDHWGPHCSNRCQCQNGALCNPITGACVCAAGFRGWRCEELCAPGTHGKGCQLPCQCRHGASCDPRAGECLCAPGYTGVYCEELCPPGSHGAHCELRCPCQNGGTCHHITGECACPPGWTGAVCAQPCPPGTFGQNCSQDCPCHHGGQCDHVTGQCHCTAGYMGDRCQEECPFGSFGFQCSQHCDCHNGGQCSPTTGACECEPGYKGPRCQERLCPEGLHGPGCTLPCPCDADNTISCHPVTGACTCQPGWSGHHCNESCPVGYYGDGCQLPCTCQNGADCHSITGGCTCAPGFMGEVCAVSCAAGTYGPNCSSICSCNNGGTCSPVDGSCTCKEGWQGLDCTLPCPSGTWGLNCNESCTCANGAACSPIDGSCSCTPGWLGDTCELPCPDGTFGLNCSEHCDCSHADGCDPVTGHCCCLAGWTGIRCDSTCPPGRWGPNCSVSCSCENGGSCSPEDGSCECAPGFRGPLCQRICPPGFYGHGCAQPCPLCVHSSRPCHHISGICECLPGFSGALCNQVCAGGYFGQDCAQLCSCANNGTCSPIDGSCQCFPGWIGKDCSQACPPGFWGPACFHACSCHNGASCSAEDGACHCTPGWTGLFCTQRCPAAFFGKDCGRVCQCQNGASCDHISGKCTCRTGFTGQHCEQRCAPGTFGYGCQQLCECMNNSTCDHVTGTCYCSPGFKGIRCDQAALMMEELNPYTKISPALGAERHSVGAVTGIMLLLFLIVVLLGLFAWHRRRQKEKGRDLAPRVSYTPAMRMTSTDYSLSGACGMDRRQNTYIMDKGFKDYMKESVCSSSTCSLNSSENPYATIKDPPILTCKLPESSYVEMKSPVHMGSPYTDVPSLSTSNKNIYEVEPTVSVVQEGCGHNSSYIQNAYDLPRNSHIPGHYDLLPVRQSPANGPSQDKQS
Proteomes:
UP000005640

Subcellular location

Subcellular Location:
Cell membrane

Function

Function:
May regulate the mosaic spacing of specific neuron subtypes in the retina through homotypic retinal neuron repulsion. Mosaics provide a mechanism to distribute each cell type evenly across the retina, ensuring that all parts of the visual field have access to a full set of processing elements (By similarity).
Gene Ontology Go:
basolateral plasma membrane
integral component of membrane
homotypic cell-cell adhesion
retina layer formation
Gene Ontology Biological Process:
homotypic cell-cell adhesion
retina layer formation
Gene Ontology Cellular Component:
basolateral plasma membrane
integral component of membrane
Keywords:
Alternative splicing
Cell membrane
Complete proteome
Disulfide bond
EGF-like domain
Glycoprotein
Membrane
Polymorphism
Reference proteome
Repeat
Signal
Transmembrane
Transmembrane helix

Publication

PubMed ID:
11347906 12975309 16572171 15489334 17974005 17498693