Names & Taxonomy

Uniprot ID:
Q9Y6B6
Entry Name:
SAR1B_HUMAN
Status:
reviewed
Protein Names:
GTP-binding protein SAR1b (GTP-binding protein B) (GTBPB)
Gene Names:
SAR1B SARA2 SARB
Gene Names Primary:
SAR1B
Organism:
Homo sapiens (Human)

Structure

Length:
198
Sequence:
MSFIFDWIYSGFSSVLQFLGLYKKTGKLVFLGLDNAGKTTLLHMLKDDRLGQHVPTLHPTSEELTIAGMTFTTFDLGGHVQARRVWKNYLPAINGIVFLVDCADHERLLESKEELDSLMTDETIANVPILILGNKIDRPEAISEERLREMFGLYGQTTGKGSISLKELNARPLEVFMCSVLKRQGYGEGFRWMAQYID
Proteomes:
UP000005640

Subcellular location

Subcellular Location:
Endoplasmic reticulum membrane

Function

Function:
Involved in transport from the endoplasmic reticulum to the Golgi apparatus. Activated by the guanine nucleotide exchange factor PREB. Involved in the selection of the protein cargo and the assembly of the COPII coat complex.
Gene Ontology Go:
cytosol
endoplasmic reticulum membrane
ER to Golgi transport vesicle membrane
Golgi cisterna membrane
GTP binding
GTPase activity
metal ion binding
antigen processing and presentation of exogenous peptide antigen via MHC class II
antigen processing and presentation of peptide antigen via MHC class I
cellular protein metabolic process
COPII vesicle coating
ER to Golgi vesicle-mediated transport
intracellular protein transport
membrane organization
post-translational protein modification
protein N-linked glycosylation via asparagine
small molecule metabolic process
Gene Ontology Biological Process:
antigen processing and presentation of exogenous peptide antigen via MHC class II
antigen processing and presentation of peptide antigen via MHC class I
cellular protein metabolic process
COPII vesicle coating
ER to Golgi vesicle-mediated transport
intracellular protein transport
membrane organization
post-translational protein modification
protein N-linked glycosylation via asparagine
small molecule metabolic process
Gene Ontology Molecular Function:
GTPase activity
GTP binding
metal ion binding
Gene Ontology Cellular Component:
cytosol
endoplasmic reticulum membrane
ER to Golgi transport vesicle membrane
Golgi cisterna membrane
Keywords:
Complete proteome
Disease mutation
ER-Golgi transport
Endoplasmic reticulum
GTP-binding
Golgi apparatus
Magnesium
Membrane
Metal-binding
Nucleotide-binding
Phosphoprotein
Protein transport
Reference proteome
Transport

Publication

PubMed ID:
15489334 21269460 24275569 12692552 17309654 19274794