Names & Taxonomy
- Uniprot ID:
- Q9Y6B6
- Entry Name:
- SAR1B_HUMAN
- Status:
- reviewed
- Protein Names:
- GTP-binding protein SAR1b (GTP-binding protein B) (GTBPB)
- Gene Names:
- SAR1B SARA2 SARB
- Gene Names Primary:
- SAR1B
- Organism:
- Homo sapiens (Human)
Structure
- Length:
- 198
- Sequence:
- MSFIFDWIYSGFSSVLQFLGLYKKTGKLVFLGLDNAGKTTLLHMLKDDRLGQHVPTLHPTSEELTIAGMTFTTFDLGGHVQARRVWKNYLPAINGIVFLVDCADHERLLESKEELDSLMTDETIANVPILILGNKIDRPEAISEERLREMFGLYGQTTGKGSISLKELNARPLEVFMCSVLKRQGYGEGFRWMAQYID
- Proteomes:
- UP000005640
Subcellular location
- Subcellular Location:
- Endoplasmic reticulum membrane
Function
- Function:
- Involved in transport from the endoplasmic reticulum to the Golgi apparatus. Activated by the guanine nucleotide exchange factor PREB. Involved in the selection of the protein cargo and the assembly of the COPII coat complex.
- Gene Ontology Go:
- cytosol
endoplasmic reticulum membrane
ER to Golgi transport vesicle membrane
Golgi cisterna membrane
GTP binding
GTPase activity
metal ion binding
antigen processing and presentation of exogenous peptide antigen via MHC class II
antigen processing and presentation of peptide antigen via MHC class I
cellular protein metabolic process
COPII vesicle coating
ER to Golgi vesicle-mediated transport
intracellular protein transport
membrane organization
post-translational protein modification
protein N-linked glycosylation via asparagine
small molecule metabolic process - Gene Ontology Biological Process:
- antigen processing and presentation of exogenous peptide antigen via MHC class II
antigen processing and presentation of peptide antigen via MHC class I
cellular protein metabolic process
COPII vesicle coating
ER to Golgi vesicle-mediated transport
intracellular protein transport
membrane organization
post-translational protein modification
protein N-linked glycosylation via asparagine
small molecule metabolic process - Gene Ontology Molecular Function:
- GTPase activity
GTP binding
metal ion binding - Gene Ontology Cellular Component:
- cytosol
endoplasmic reticulum membrane
ER to Golgi transport vesicle membrane
Golgi cisterna membrane - Keywords:
- Complete proteome
Disease mutation
ER-Golgi transport
Endoplasmic reticulum
GTP-binding
Golgi apparatus
Magnesium
Membrane
Metal-binding
Nucleotide-binding
Phosphoprotein
Protein transport
Reference proteome
Transport