Names & Taxonomy
- Uniprot ID:
- Q9UKZ9
- Entry Name:
- PCOC2_HUMAN
- Status:
- reviewed
- Protein Names:
- Procollagen C-endopeptidase enhancer 2 (Procollagen COOH-terminal proteinase enhancer 2) (PCPE-2) (Procollagen C-proteinase enhancer 2)
- Gene Names:
- PCOLCE2 PCPE2 UNQ250/PRO287
- Gene Names Orf:
- UNQ250/PRO287
- Gene Names Primary:
- PCOLCE2
- Organism:
- Homo sapiens (Human)
Structure
- Length:
- 415
- Sequence:
- MRGANAWAPLCLLLAAATQLSRQQSPERPVFTCGGILTGESGFIGSEGFPGVYPPNSKCTWKITVPEGKVVVLNFRFIDLESDNLCRYDFVDVYNGHANGQRIGRFCGTFRPGALVSSGNKMMVQMISDANTAGNGFMAMFSAAEPNERGDQYCGGLLDRPSGSFKTPNWPDRDYPAGVTCVWHIVAPKNQLIELKFEKFDVERDNYCRYDYVAVFNGGEVNDARRIGKYCGDSPPAPIVSERNELLIQFLSDLSLTADGFIGHYIFRPKKLPTTTEQPVTTTFPVTTGLKPTVALCQQKCRRTGTLEGNYCSSDFVLAGTVITTITRDGSLHATVSIINIYKEGNLAIQQAGKNMSARLTVVCKQCPLLRRGLNYIIMGQVGEDGRGKIMPNSFIMMFKTKNQKLLDALKNKQC
- Proteomes:
- UP000005640
Subcellular location
- Subcellular Location:
- Secreted
Function
- Function:
- Binds to the C-terminal propeptide of types I and II procollagens and may enhance the cleavage of that propeptide by BMP1.
- Gene Ontology Go:
- extracellular exosome
collagen binding
heparin binding
peptidase activator activity
positive regulation of peptidase activity - Gene Ontology Biological Process:
- positive regulation of peptidase activity
- Gene Ontology Molecular Function:
- collagen binding
heparin binding
peptidase activator activity - Gene Ontology Cellular Component:
- extracellular exosome
- Keywords:
- Complete proteome
Direct protein sequencing
Disulfide bond
Glycoprotein
Heparin-binding
Polymorphism
Reference proteome
Repeat
Secreted
Signal