Names & Taxonomy
- Uniprot ID:
- Q9UKF2
- Entry Name:
- ADA30_HUMAN
- Status:
- reviewed
- Protein Names:
- Disintegrin and metalloproteinase domain-containing protein 30 (ADAM 30) (EC 3.4.24.-)
- Gene Names:
- ADAM30 UNQ2509/PRO5997
- Gene Names Orf:
- UNQ2509/PRO5997
- Gene Names Primary:
- ADAM30
- Organism:
- Homo sapiens (Human)
Structure
- Length:
- 790
- Sequence:
- MRSVQIFLSQCRLLLLLVPTMLLKSLGEDVIFHPEGEFDSYEVTIPEKLSFRGEVQGVVSPVSYLLQLKGKKHVLHLWPKRLLLPRHLRVFSFTEHGELLEDHPYIPKDCNYMGSVKESLDSKATISTCMGGLRGVFNIDAKHYQIEPLKASPSFEHVVYLLKKEQFGNQVCGLSDDEIEWQMAPYENKARLRDFPGSYKHPKYLELILLFDQSRYRFVNNNLSQVIHDAILLTGIMDTYFQDVRMRIHLKALEVWTDFNKIRVGYPELAEVLGRFVIYKKSVLNARLSSDWAHLYLQRKYNDALAWSFGKVCSLEYAGSVSTLLDTNILAPATWSAHELGHAVGMSHDEQYCQCRGRLNCIMGSGRTGFSNCSYISFFKHISSGATCLNNIPGLGYVLKRCGNKIVEDNEECDCGSTEECQKDRCCQSNCKLQPGANCSIGLCCHDCRFRPSGYVCRQEGNECDLAEYCDGNSSSCPNDVYKQDGTPCKYEGRCFRKGCRSRYMQCQSIFGPDAMEAPSECYDAVNLIGDQFGNCEITGIRNFKKCESANSICGRLQCINVETIPDLPEHTTIISTHLQAENLMCWGTGYHLSMKPMGIPDLGMINDGTSCGEGRVCFKKNCVNSSVLQFDCLPEKCNTRGVCNNRKNCHCMYGWAPPFCEEVGYGGSIDSGPPGLLRGAIPSSIWVVSIIMFRLILLILSVVFVFFRQVIGNHLKPKQEKMPLSKAKTEQEESKTKTVQEESKTKTGQEESEAKTGQEESKAKTGQEESKANIESKRPKAKSVKKQKK
- Proteomes:
- UP000005640
Subcellular location
- Subcellular Location:
- Membrane; Single-pass type I membrane protein.
Function
- Function:
- May be involved in spermatogenesis and fertilization.
- Cofactor:
- COFACTOR: Name=Zn(2+); Xref=ChEBI:CHEBI:29105;
- Active Site:
- ACT_SITE 339 339
- Gene Ontology Go:
- integral component of membrane
plasma membrane
metalloendopeptidase activity
metallopeptidase activity
zinc ion binding
binding of sperm to zona pellucida
multicellular organism reproduction
single fertilization - Gene Ontology Biological Process:
- binding of sperm to zona pellucida
multicellular organism reproduction
single fertilization - Gene Ontology Molecular Function:
- metalloendopeptidase activity
metallopeptidase activity
zinc ion binding - Gene Ontology Cellular Component:
- integral component of membrane
plasma membrane - Keywords:
- Alternative splicing
Complete proteome
Disulfide bond
EGF-like domain
Glycoprotein
Hydrolase
Membrane
Metal-binding
Metalloprotease
Polymorphism
Protease
Reference proteome
Repeat
Signal
Transmembrane
Transmembrane helix
Zinc
Zymogen