Names & Taxonomy
- Uniprot ID:
- Q9UFY1
- Entry Name:
- Q9UFY1_HUMAN
- Status:
- unreviewed
- Protein Names:
- Phosphoinositide phospholipase C (EC 3.1.4.11) (Fragment)
- Gene Names:
- DKFZp434N101
- Gene Names Primary:
- DKFZp434N101
- Organism:
- Homo sapiens (Human)
Structure
- Length:
- 629
- Sequence:
- RVQQEGQTVMLGNSEFDSLVDLISYYEKHPLYRKMKLRYPINEEALEKIGTAEPDYGALYEGRNPGFYVEANPMPTFKCAVKALFDYKAQREDELTFTKSAIIQNVEKQEGGWWRGDYGGKKQLWFPSNYVEEMVNPVALEPEREHLDENSPLGDLLRGVLDVPACQIAIRPEGKNNRLFVFSISMASVAHWSLDVAADSQEELQDWVKKIREVAQTADARLTEGKIMERRKKIALELSELVVYCRPVPFDEEKIGTERACYRDMSSFPETKAEKYVNKAKGKKFLQYNRLQLSRIYPKGQRLDSSNYDPLPMWICGSQLVALNFQTPDKPMQMNQALFMTGRHCGYVLQPSTMRDEAFDPFDKSSLRGLEPCAISIEVLGARHLPKNGRGIVCPFVEIEVAGAEYDSTKQKTEFVVDNGLNPVWPAKPFHFQISNPEFAFLRFVVYEEDMFSDQNFLAQATFPVKGLKTGYRAVPLKNNYSEDLELASLLIKIDIFPAKQENGDLSPFSGTSLRERGSDASGQLFHGRAREGSFESRYQQPFEDFRISQEHLADHFDSRERSKDTLPFCPGPQEGLGSMETTASSCTPASLESSRCCAPCRMPRTGFFGSSPLWRPSGSRSLKPGFQQ
Function
- Catalytic Activity:
- 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate + H(2)O = 1D-myo-inositol 1,4,5-trisphosphate + diacylglycerol.
- Gene Ontology Go:
- intracellular
phosphatidylinositol phospholipase C activity
signal transducer activity
intracellular signal transduction
lipid catabolic process - Gene Ontology Biological Process:
- intracellular signal transduction
lipid catabolic process - Gene Ontology Molecular Function:
- phosphatidylinositol phospholipase C activity
signal transducer activity - Gene Ontology Cellular Component:
- intracellular
- Keywords:
- Hydrolase
Lipid degradation
Lipid metabolism
SH3 domain
Transducer