Names & Taxonomy
- Uniprot ID:
- Q9UBX3
- Entry Name:
- DIC_HUMAN
- Status:
- reviewed
- Protein Names:
- Mitochondrial dicarboxylate carrier (Solute carrier family 25 member 10)
- Gene Names:
- SLC25A10 DIC
- Gene Names Primary:
- SLC25A10
- Organism:
- Homo sapiens (Human)
Structure
- Length:
- 287
- Sequence:
- MAAEARVSRWYFGGLASCGAACCTHPLDLLKVHLQTQQEVKLRMTGMALRVVRTDGILALYSGLSASLCRQMTYSLTRFAIYETVRDRVAKGSQGPLPFHEKVLLGSVSGLAGGFVGTPADLVNVRMQNDVKLPQGQRRNYAHALDGLYRVAREEGLRRLFSGATMASSRGALVTVGQLSCYDQAKQLVLSTGYLSDNIFTHFVASFIAGGCATFLCQPLDVLKTRLMNSKGEYQGVFHCAVETAKLGPLAFYKGLVPAGIRLIPHTVLTFVFLEQLRKNFGIKVPS
- Proteomes:
- UP000005640
Subcellular location
- Subcellular Location:
- Mitochondrion inner membrane; Multi-pass membrane protein.
Function
- Function:
- Involved in translocation of malonate, malate and succinate in exchange for phosphate, sulfate, sulfite or thiosulfate across mitochondrial inner membrane.
- Cross Reference Drug Bank:
- DB00139
- Gene Ontology Go:
- integral component of membrane
mitochondrial inner membrane
nucleus
dicarboxylic acid transmembrane transporter activity
structural constituent of ribosome
carbohydrate metabolic process
cellular nitrogen compound metabolic process
dicarboxylic acid transport
gluconeogenesis
glucose metabolic process
ion transport
mitochondrial transport
small molecule metabolic process
sulfide oxidation, using sulfide:quinone oxidoreductase
sulfur amino acid catabolic process
sulfur amino acid metabolic process
translation
transmembrane transport - Gene Ontology Biological Process:
- carbohydrate metabolic process
cellular nitrogen compound metabolic process
dicarboxylic acid transport
gluconeogenesis
glucose metabolic process
ion transport
mitochondrial transport
small molecule metabolic process
sulfide oxidation, using sulfide:quinone oxidoreductase
sulfur amino acid catabolic process
sulfur amino acid metabolic process
translation
transmembrane transport - Gene Ontology Molecular Function:
- dicarboxylic acid transmembrane transporter activity
structural constituent of ribosome - Gene Ontology Cellular Component:
- integral component of membrane
mitochondrial inner membrane
nucleus - Keywords:
- Alternative splicing
Complete proteome
Membrane
Mitochondrion
Mitochondrion inner membrane
Reference proteome
Repeat
Transmembrane
Transmembrane helix
Transport - Interacts With:
- Q6A162; P60410; Q9BYR5; P26371; Q99750; Q7Z3S9