Names & Taxonomy
- Uniprot ID:
- Q9UBH6
- Entry Name:
- XPR1_HUMAN
- Status:
- reviewed
- Protein Names:
- Xenotropic and polytropic retrovirus receptor 1 (Protein SYG1 homolog) (Xenotropic and polytropic murine leukemia virus receptor X3) (X-receptor)
- Gene Names:
- XPR1 SYG1 XR
- Gene Names Primary:
- XPR1
- Organism:
- Homo sapiens (Human)
Structure
- Length:
- 696
- Sequence:
- MKFAEHLSAHITPEWRKQYIQYEAFKDMLYSAQDQAPSVEVTDEDTVKRYFAKFEEKFFQTCEKELAKINTFYSEKLAEAQRRFATLQNELQSSLDAQKESTGVTTLRQRRKPVFHLSHEERVQHRNIKDLKLAFSEFYLSLILLQNYQNLNFTGFRKILKKHDKILETSRGADWRVAHVEVAPFYTCKKINQLISETEAVVTNELEDGDRQKAMKRLRVPPLGAAQPAPAWTTFRVGLFCGIFIVLNITLVLAAVFKLETDRSIWPLIRIYRGGFLLIEFLFLLGINTYGWRQAGVNHVLIFELNPRSNLSHQHLFEIAGFLGILWCLSLLACFFAPISVIPTYVYPLALYGFMVFFLINPTKTFYYKSRFWLLKLLFRVFTAPFHKVGFADFWLADQLNSLSVILMDLEYMICFYSLELKWDESKGLLPNNSEESGICHKYTYGVRAIVQCIPAWLRFIQCLRRYRDTKRAFPHLVNAGKYSTTFFMVTFAALYSTHKERGHSDTMVFFYLWIVFYIISSCYTLIWDLKMDWGLFDKNAGENTFLREEIVYPQKAYYYCAIIEDVILRFAWTIQISITSTTLLPHSGDIIATVFAPLEVFRRFVWNFFRLENEHLNNCGEFRAVRDISVAPLNADDQTLLEQMMDQDDGVRNRQKNRSWKYNQSISLRRPRLASQSKARDTKVLIEDTDDEANT
- Proteomes:
- UP000005640
Subcellular location
- Subcellular Location:
- Cell membrane
Function
- Function:
- Plays a role in phosphate homeostasis. Mediates phosphate export from the cell (PubMed:25938945). May function in G-protein coupled signal transduction (By similarity).
- Gene Ontology Go:
- Golgi apparatus
integral component of plasma membrane
plasma membrane
G-protein coupled receptor activity
receptor activity
transmembrane signaling receptor activity
virus receptor activity
cellular phosphate ion homeostasis
G-protein coupled receptor signaling pathway
response to virus - Gene Ontology Biological Process:
- cellular phosphate ion homeostasis
G-protein coupled receptor signaling pathway
response to virus - Gene Ontology Molecular Function:
- G-protein coupled receptor activity
receptor activity
transmembrane signaling receptor activity
virus receptor activity - Gene Ontology Cellular Component:
- Golgi apparatus
integral component of plasma membrane
plasma membrane - Keywords:
- Alternative splicing
Cell membrane
Complete proteome
Disease mutation
Host cell receptor for virus entry
Membrane
Phosphoprotein
Polymorphism
Receptor
Reference proteome
Transmembrane
Transmembrane helix