Names & Taxonomy
- Uniprot ID:
- Q9P1W3
- Entry Name:
- CSC1_HUMAN
- Status:
- reviewed
- Protein Names:
- Calcium permeable stress-gated cation channel 1 (Transmembrane protein 63C)
- Gene Names:
- TMEM63C C14orf171 CSC1
- Gene Names Primary:
- TMEM63C
- Organism:
- Homo sapiens (Human)
Structure
- Length:
- 806
- Sequence:
- MSASPDDLSTGGRLQNMTVDECFQSRNTVLQGQPFGGVPTVLCLNIALWVLVLVVYSFLRKAAWDYGRLALLIHNDSLTSLIYGEQSEKTSPSETSLEMERRDKGFCSWFFNSITMKDEDLINKCGDDARIYIVFQYHLIIFVLIICIPSLGIILPINYTGSVLDWSSHFARTTIVNVSTESKLLWLHSLLSFFYFITNFMFMAHHCLGFAPRNSQKVTRTLMITYVPKDIEDPELIIKHFHEAYPGSVVTRVHFCYDVRNLIDLDDQRRHAMRGRLFYTAKAKKTGKVMIRIHPCARLCFCKCWTCFKEVDAEQYYSELEEQLTDEFNAELNRVPLKRLDLIFVTFQDSRMAKRVRKDYKYVQCGVQPQQSSVTTIVKSYYWRVTMAPHPKDIIWKHLSVRRFFWWARFIAINTFLFFLFFFLTTPAIIMNTIDMYNVTRPIEKLQNPIVTQFFPSVMLWGFTVILPLIVYFSAFLEAHWTRSSQNLVMVHKCYIFLVFMVVILPSMGLTSLDVFLRWLFDIYYLEQASIRFQCVFLPDNGAFFVNYVITAALLGTGMELLRLGSLFCYSTRLFFSRSEPERVNIRKNQAIDFQFGREYAWMMNVFSVVMAYSITCPIIVPFGLLYLCMKHLTDRYNMYYSFAPTKLNEQIHMAAVSQAIFAPLLGLFWMLFFSILRLGSLHAITIFSLSTLLIAMVIAFVGIFLGKLRMVADYEPEEEEIQTVFDMEPSSTSSTPTSLLYVATVLQEPELNLTPASSPARHTYGTMNNQPEEGEEESGLRGFARELDSAQFQEGLELEGQNQYH
- Proteomes:
- UP000005640
Subcellular location
- Subcellular Location:
- Membrane
Function
- Function:
- Acts as an osmosensitive calcium-permeable cation channel.
- Enzyme Regulation:
- ENZYME REGULATION: Activated by hyperosmotic shock after mannitol treatment.
- Gene Ontology Go:
- integral component of membrane
calcium activated cation channel activity
cation transmembrane transport
cation transport - Gene Ontology Biological Process:
- cation transmembrane transport
cation transport - Gene Ontology Molecular Function:
- calcium activated cation channel activity
- Gene Ontology Cellular Component:
- integral component of membrane
- Keywords:
- Calcium
Complete proteome
Ion channel
Ion transport
Membrane
Phosphoprotein
Polymorphism
Reference proteome
Transmembrane
Transmembrane helix
Transport