Names & Taxonomy

Uniprot ID:
Q9P1P4
Entry Name:
TAAR3_HUMAN
Status:
reviewed
Protein Names:
Putative trace amine-associated receptor 3 (TaR-3) (Trace amine receptor 3) (hTaar3) (G-protein coupled receptor 57)
Gene Names:
TAAR3 GPR57
Gene Names Primary:
TAAR3
Organism:
Homo sapiens (Human)

Structure

Length:
343
Sequence:
MDLTYIPEDLSSCPKFVNKILSSHQPLFSCPGDNVFGYDWSHDYPLFGNLVIMVSISHFKQLHSPTNFLILSMATTDFLLGFVIMPYSIMRSVESCWYFGDGFCKFHTSFDMMLRLTSIFHLCSIAIDRFYAVCYPLHYTTKMTNSTIKQLLAFCWSVPALFSFGLVLSEADVSGMQSYKILVACFNFCALTFNKFWGTILFTTCFFTPGSIMVGIYGKIFIVSKQHARVISHVPENTKGAVKKHLSKKKDRKAAKTLGIVMGVFLACWLPCFLAVLIDPYLDYSTPILILDLLVWLRYFNSTCNPLIHGFFNPWFQKAFKYIVSGKIFSSHSETANLFPEAH
Proteomes:
UP000005640

Subcellular location

Subcellular Location:
Cell membrane

Function

Function:
Olfactory receptor activated by several primary trace amines, including isoamylamine. Activated by isoamylamine and cyclohexylamine, but not to the corresponding alcohols, isoamylalcohol and cyclohexanol. This receptor is probably mediated by the G(s)-class of G-proteins which activate adenylate cyclase (By similarity).
Gene Ontology Go:
integral component of membrane
plasma membrane
G-protein coupled receptor activity
trace-amine receptor activity
sensory perception of chemical stimulus
Gene Ontology Biological Process:
sensory perception of chemical stimulus
Gene Ontology Molecular Function:
G-protein coupled receptor activity
trace-amine receptor activity
Gene Ontology Cellular Component:
integral component of membrane
plasma membrane
Keywords:
Cell membrane
Complete proteome
Disulfide bond
G-protein coupled receptor
Glycoprotein
Membrane
Receptor
Reference proteome
Transducer
Transmembrane
Transmembrane helix

Publication

PubMed ID:
10684976