Names & Taxonomy
- Uniprot ID:
- Q9NYX4
- Entry Name:
- CALY_HUMAN
- Status:
- reviewed
- Protein Names:
- Neuron-specific vesicular protein calcyon
- Gene Names:
- CALY DRD1IP
- Gene Names Primary:
- CALY
- Organism:
- Homo sapiens (Human)
Structure
- Length:
- 217
- Sequence:
- MVKLGCSFSGKPGKDPGDQDGAAMDSVPLISPLDISQLQPPLPDQVVIKTQTEYQLSSPDQQNFPDLEGQRLNCSHPEEGRRLPTARMIAFAMALLGCVLIMYKAIWYDQFTCPDGFLLRHKICTPLTLEMYYTEMDPERHRSILAAIGAYPLSRKHGTETPAAWGDGYRAAKEERKGPTQAGAAAAATEPPGKPSAKAEKEAARKAAGSAAPPPAQ
- Proteomes:
- UP000005640
Subcellular location
- Subcellular Location:
- Cytoplasmic vesicle membrane; Single-pass membrane protein. Cell membrane; Single-pass membrane protein.
Function
- Function:
- Interacts with clathrin light chain A and stimulates clathrin self-assembly and clathrin-mediated endocytosis.
- Cross Reference Drug Bank:
- DB00714 DB00363 DB00831
- Gene Ontology Go:
- cytoplasmic vesicle
cytoplasmic vesicle membrane
integral component of plasma membrane
clathrin light chain binding
clathrin coat assembly
dopamine receptor signaling pathway
endocytosis
positive regulation of endocytosis - Gene Ontology Biological Process:
- clathrin coat assembly
dopamine receptor signaling pathway
endocytosis
positive regulation of endocytosis - Gene Ontology Molecular Function:
- clathrin light chain binding
- Gene Ontology Cellular Component:
- cytoplasmic vesicle
cytoplasmic vesicle membrane
integral component of plasma membrane - Keywords:
- Alternative splicing
Cell membrane
Complete proteome
Cytoplasmic vesicle
Endocytosis
Glycoprotein
Membrane
Reference proteome
Transmembrane
Transmembrane helix - Interacts With:
- P09496