Names & Taxonomy

Uniprot ID:
Q9NYW1
Entry Name:
TA2R9_HUMAN
Status:
reviewed
Protein Names:
Taste receptor type 2 member 9 (T2R9) (Taste receptor family B member 6) (TRB6)
Gene Names:
TAS2R9
Gene Names Primary:
TAS2R9
Organism:
Homo sapiens (Human)

Structure

Length:
312
Sequence:
MPSAIEAIYIILIAGELTIGIWGNGFIVLVNCIDWLKRRDISLIDIILISLAISRICLLCVISLDGFFMLLFPGTYGNSVLVSIVNVVWTFANNSSLWFTSCLSIFYLLKIANISHPFFFWLKLKINKVMLAILLGSFLISLIISVPKNDDMWYHLFKVSHEENITWKFKVSKIPGTFKQLTLNLGVMVPFILCLISFFLLLFSLVRHTKQIRLHATGFRDPSTEAHMRAIKAVIIFLLLLIVYYPVFLVMTSSALIPQGKLVLMIGDIVTVIFPSSHSFILIMGNSKLREAFLKMLRFVKCFLRRRKPFVP
Proteomes:
UP000005640

Subcellular location

Subcellular Location:
Membrane; Multi-pass membrane protein.

Function

Function:
Gustducin-coupled receptor implicated in the perception of bitter compounds in the oral cavity and the gastrointestinal tract. Signals through PLCB2 and the calcium-regulated cation channel TRPM5 (By similarity).
Gene Ontology Go:
integral component of membrane
plasma membrane
taste receptor activity
detection of chemical stimulus involved in sensory perception of taste
Gene Ontology Biological Process:
detection of chemical stimulus involved in sensory perception of taste
Gene Ontology Molecular Function:
taste receptor activity
Gene Ontology Cellular Component:
integral component of membrane
plasma membrane
Keywords:
Complete proteome
G-protein coupled receptor
Glycoprotein
Membrane
Polymorphism
Receptor
Reference proteome
Sensory transduction
Taste
Transducer
Transmembrane
Transmembrane helix

Publication

PubMed ID:
10761934 15496549 15489334 15744053 10761935 12139982 11696554 12581520