Names & Taxonomy
- Uniprot ID:
- Q9NYW0
- Entry Name:
- T2R10_HUMAN
- Status:
- reviewed
- Protein Names:
- Taste receptor type 2 member 10 (T2R10) (Taste receptor family B member 2) (TRB2)
- Gene Names:
- TAS2R10
- Gene Names Primary:
- TAS2R10
- Organism:
- Homo sapiens (Human)
Structure
- Length:
- 307
- Sequence:
- MLRVVEGIFIFVVVSESVFGVLGNGFIGLVNCIDCAKNKLSTIGFILTGLAISRIFLIWIIITDGFIQIFSPNIYASGNLIEYISYFWVIGNQSSMWFATSLSIFYFLKIANFSNYIFLWLKSRTNMVLPFMIVFLLISSLLNFAYIAKILNDYKTKNDTVWDLNMYKSEYFIKQILLNLGVIFFFTLSLITCIFLIISLWRHNRQMQSNVTGLRDSNTEAHVKAMKVLISFIILFILYFIGMAIEISCFTVRENKLLLMFGMTTTAIYPWGHSFILILGNSKLKQASLRVLQQLKCCEKRKNLRVT
- Proteomes:
- UP000005640
Subcellular location
- Subcellular Location:
- Membrane; Multi-pass membrane protein.
Function
- Function:
- Gustducin-coupled strychnine receptor implicated in the perception of bitter compounds in the oral cavity and the gastrointestinal tract. Signals through PLCB2 and the calcium-regulated cation channel TRPM5.
- Gene Ontology Go:
- integral component of membrane
plasma membrane
bitter taste receptor activity
taste receptor activity
detection of chemical stimulus involved in sensory perception of bitter taste - Gene Ontology Biological Process:
- detection of chemical stimulus involved in sensory perception of bitter taste
- Gene Ontology Molecular Function:
- bitter taste receptor activity
taste receptor activity - Gene Ontology Cellular Component:
- integral component of membrane
plasma membrane - Keywords:
- Complete proteome
G-protein coupled receptor
Glycoprotein
Membrane
Polymorphism
Receptor
Reference proteome
Sensory transduction
Taste
Transducer
Transmembrane
Transmembrane helix