Names & Taxonomy
- Uniprot ID:
- Q9NTF0
- Entry Name:
- Q9NTF0_HUMAN
- Status:
- unreviewed
- Protein Names:
- Cystathionine beta-synthase (EC 4.2.1.22) (Fragment)
- Gene Names:
- DKFZp727E011
- Gene Names Primary:
- DKFZp727E011
- Organism:
- Homo sapiens (Human)
Structure
- Length:
- 475
- Sequence:
- RPDILKKIGDTPMVRINKIGKKFGLKCELLAKCEFFNAGGSVKDRISLRMIEDAERDGTLKPGDTIIEPTSGNTGIGLALAAAVRGYRCIIVMPEKMSSEKVDVLRALGAEIVRTPTNARFDSPESHVGVAWRLKNEIPNSHILDQYRNASNPLPHYDTTADEILQQCDGKLDMLVASVGTGGTITGIARKLKEKCPGCRIIGVDPEGSILAEPEELNQTEQTTYEVEGIGYDFIPTVLDRTVVDKWFKSNDEEAFTLARMLIAQEGLLCGGSAGSTVAVAVKAAQELQEGQRCVVILPDSVRNYMTKFLSDRWMLQKGFLKEEDLTEKKPWWWHLRVQELGLSAPLTVLPTITCGHTIEILREKGFDQAPVVDEAGVILGMVTLGNMLSSLLAGKVQPSDQVGKVIYKQFKQIRLTDTLGRLSHILEMDHFALVVHEQIQYHSTGKSSQRQMVFGVVTAIDLLNFVAAQERDQK
Function
- Catalytic Activity:
- L-serine + L-homocysteine = L-cystathionine + H(2)O.
- Cofactor:
- COFACTOR: Name=pyridoxal 5'-phosphate; Xref=ChEBI:CHEBI:597326;
- Gene Ontology Go:
- cytoplasm
cystathionine beta-synthase activity
cysteine biosynthetic process from serine
cysteine biosynthetic process via cystathionine - Gene Ontology Biological Process:
- cysteine biosynthetic process from serine
cysteine biosynthetic process via cystathionine - Gene Ontology Molecular Function:
- cystathionine beta-synthase activity
- Gene Ontology Cellular Component:
- cytoplasm
- Keywords:
- Amino-acid biosynthesis
CBS domain
Cysteine biosynthesis
Lyase
Pyridoxal phosphate