Names & Taxonomy
- Uniprot ID:
- Q9NRX5
- Entry Name:
- SERC1_HUMAN
- Status:
- reviewed
- Protein Names:
- Serine incorporator 1 (Tumor differentially expressed protein 1-like) (Tumor differentially expressed protein 2)
- Gene Names:
- SERINC1 KIAA1253 TDE1L TDE2 UNQ396/PRO732
- Gene Names Orf:
- UNQ396/PRO732
- Gene Names Primary:
- SERINC1
- Organism:
- Homo sapiens (Human)
Structure
- Length:
- 453
- Sequence:
- MGSVLGLCSMASWIPCLCGSAPCLLCRCCPSGNNSTVTRLIYALFLLVGVCVACVMLIPGMEEQLNKIPGFCENEKGVVPCNILVGYKAVYRLCFGLAMFYLLLSLLMIKVKSSSDPRAAVHNGFWFFKFAAAIAIIIGAFFIPEGTFTTVWFYVGMAGAFCFILIQLVLLIDFAHSWNESWVEKMEEGNSRCWYAALLSATALNYLLSLVAIVLFFVYYTHPASCSENKAFISVNMLLCVGASVMSILPKIQESQPRSGLLQSSVITVYTMYLTWSAMTNEPETNCNPSLLSIIGYNTTSTVPKEGQSVQWWHAQGIIGLILFLLCVFYSSIRTSNNSQVNKLTLTSDESTLIEDGGARSDGSLEDGDDVHRAVDNERDGVTYSYSFFHFMLFLASLYIMMTLTNWYRYEPSREMKSQWTAVWVKISSSWIGIVLYVWTLVAPLVLTNRDFD
- Proteomes:
- UP000005640
Subcellular location
- Subcellular Location:
- Endoplasmic reticulum membrane
Function
- Function:
- Enhances the incorporation of serine into phosphatidylserine and sphingolipids.
- Gene Ontology Go:
- endoplasmic reticulum membrane
extracellular exosome
integral component of membrane
plasma membrane
L-serine transmembrane transporter activity
L-serine transport
phosphatidylserine metabolic process
phospholipid biosynthetic process
positive regulation of CDP-diacylglycerol-serine O-phosphatidyltransferase activity
positive regulation of serine C-palmitoyltransferase activity
sphingolipid metabolic process - Gene Ontology Biological Process:
- L-serine transport
phosphatidylserine metabolic process
phospholipid biosynthetic process
positive regulation of CDP-diacylglycerol-serine O-phosphatidyltransferase activity
positive regulation of serine C-palmitoyltransferase activity
sphingolipid metabolic process - Gene Ontology Molecular Function:
- L-serine transmembrane transporter activity
- Gene Ontology Cellular Component:
- endoplasmic reticulum membrane
extracellular exosome
integral component of membrane
plasma membrane - Keywords:
- Complete proteome
Endoplasmic reticulum
Glycoprotein
Lipid biosynthesis
Lipid metabolism
Lipoprotein
Membrane
Myristate
Phospholipid biosynthesis
Phospholipid metabolism
Phosphoprotein
Polymorphism
Reference proteome
Transmembrane
Transmembrane helix - Interacts With:
- Q06710