Names & Taxonomy
- Uniprot ID:
- Q9NPC2
- Entry Name:
- KCNK9_HUMAN
- Status:
- reviewed
- Protein Names:
- Potassium channel subfamily K member 9 (Acid-sensitive potassium channel protein TASK-3) (TWIK-related acid-sensitive K(+) channel 3) (Two pore potassium channel KT3.2) (Two pore K(+) channel KT3.2)
- Gene Names:
- KCNK9 TASK3
- Gene Names Primary:
- KCNK9
- Organism:
- Homo sapiens (Human)
Structure
- Length:
- 374
- Sequence:
- MKRQNVRTLSLIVCTFTYLLVGAAVFDALESDHEMREEEKLKAEEIRIKGKYNISSEDYRQLELVILQSEPHRAGVQWKFAGSFYFAITVITTIGYGHAAPGTDAGKAFCMFYAVLGIPLTLVMFQSLGERMNTFVRYLLKRIKKCCGMRNTDVSMENMVTVGFFSCMGTLCIGAAAFSQCEEWSFFHAYYYCFITLTTIGFGDYVALQTKGALQKKPLYVAFSFMYILVGLTVIGAFLNLVVLRFLTMNSEDERRDAEERASLAGNRNSMVIHIPEEPRPSRPRYKADVPDLQSVCSCTCYRSQDYGGRSVAPQNSFSAKLAPHYFHSISYKIEEISPSTLKNSLFPSPISSISPGLHSFTDHQRLMKRRKSV
- Proteomes:
- UP000005640
Subcellular location
- Subcellular Location:
- Cell membrane
- Intramembrane:
- INTRAMEM 89 101 Pore-forming; Name=Pore-forming 1.
Function
- Function:
- pH-dependent, voltage-insensitive, background potassium channel protein.
- Cross Reference Drug Bank:
- DB00561 DB01159
- Gene Ontology Go:
- integral component of plasma membrane
plasma membrane
synaptic vesicle
potassium ion leak channel activity
voltage-gated potassium channel activity
potassium ion transmembrane transport
potassium ion transport
stabilization of membrane potential
synaptic transmission - Gene Ontology Biological Process:
- potassium ion transmembrane transport
potassium ion transport
stabilization of membrane potential
synaptic transmission - Gene Ontology Molecular Function:
- potassium ion leak channel activity
voltage-gated potassium channel activity - Gene Ontology Cellular Component:
- integral component of plasma membrane
plasma membrane
synaptic vesicle - Keywords:
- 3D-structure
Cell membrane
Complete proteome
Disease mutation
Glycoprotein
Ion channel
Ion transport
Membrane
Mental retardation
Potassium
Potassium channel
Potassium transport
Reference proteome
Transmembrane
Transmembrane helix
Transport