Names & Taxonomy
- Uniprot ID:
- Q9HCP6
- Entry Name:
- HHATL_HUMAN
- Status:
- reviewed
- Protein Names:
- Protein-cysteine N-palmitoyltransferase HHAT-like protein (Glycerol uptake/transporter homolog) (Hedgehog acyltransferase-like protein)
- Gene Names:
- HHATL C3orf3 GUP1 KIAA1173
- Gene Names Primary:
- HHATL
- Organism:
- Homo sapiens (Human)
Structure
- Length:
- 504
- Sequence:
- MGIKTALPAAELGLYSLVLSGALAYAGRGLLEASQDGAHRKAFRESVRPGWEYIGRKMDVADFEWVMWFTSFRNVIIFALSGHVLFAKLCTMVAPKLRSWMYAVYGALAVMGTMGPWYLLLLLGHCVGLYVASLLGQPWLCLGLGLASLASFKMDPLISWQSGFVTGTFDLQEVLFHGGSSFTVLRCTSFALESCAHPDRHYSLADLLKYNFYLPFFFFGPIMTFDRFHAQVSQVEPVRREGELWHIRAQAGLSVVAIMAVDIFFHFFYILTIPSDLKFANRLPDSALAGLAYSNLVYDWVKAAVLFGVVNTVACLDHLDPPQPPKCITALYVFAETHFDRGINDWLCKYVYNHIGGEHSAVIPELAATVATFAITTLWLGPCDIVYLWSFLNCFGLNFELWMQKLAEWGPLARIEASLSVQMSRRVRALFGAMNFWAIIMYNLVSLNSLKFTELVARRLLLTGFPQTTLSILFVTYCGVQLVKERERTLALEEEQKQDKEKPE
- Proteomes:
- UP000005640
Subcellular location
- Subcellular Location:
- Endoplasmic reticulum membrane
Function
- Function:
- Negatively regulates N-terminal palmitoylation of SHH by HHAT/SKN.
- Gene Ontology Go:
- endoplasmic reticulum
endoplasmic reticulum membrane
integral component of membrane
perinuclear region of cytoplasm
negative regulation of N-terminal protein palmitoylation - Gene Ontology Biological Process:
- negative regulation of N-terminal protein palmitoylation
- Gene Ontology Cellular Component:
- endoplasmic reticulum
endoplasmic reticulum membrane
integral component of membrane
perinuclear region of cytoplasm - Keywords:
- Complete proteome
Endoplasmic reticulum
Membrane
Polymorphism
Reference proteome
Transmembrane
Transmembrane helix