Names & Taxonomy
- Uniprot ID:
- Q9HCJ1
- Entry Name:
- ANKH_HUMAN
- Status:
- reviewed
- Protein Names:
- Progressive ankylosis protein homolog (ANK)
- Gene Names:
- ANKH KIAA1581 UNQ241/PRO274
- Gene Names Orf:
- UNQ241/PRO274
- Gene Names Primary:
- ANKH
- Organism:
- Homo sapiens (Human)
Structure
- Length:
- 492
- Sequence:
- MVKFPALTHYWPLIRFLVPLGITNIAIDFGEQALNRGIAAVKEDAVEMLASYGLAYSLMKFFTGPMSDFKNVGLVFVNSKRDRTKAVLCMVVAGAIAAVFHTLIAYSDLGYYIINKLHHVDESVGSKTRRAFLYLAAFPFMDAMAWTHAGILLKHKYSFLVGCASISDVIAQVVFVAILLHSHLECREPLLIPILSLYMGALVRCTTLCLGYYKNIHDIIPDRSGPELGGDATIRKMLSFWWPLALILATQRISRPIVNLFVSRDLGGSSAATEAVAILTATYPVGHMPYGWLTEIRAVYPAFDKNNPSNKLVSTSNTVTAAHIKKFTFVCMALSLTLCFVMFWTPNVSEKILIDIIGVDFAFAELCVVPLRIFSFFPVPVTVRAHLTGWLMTLKKTFVLAPSSVLRIIVLIASLVVLPYLGVHGATLGVGSLLAGFVGESTMVAIAACYVYRKQKKKMENESATEGEDSAMTDMPPTEEVTDIVEMREENE
- Proteomes:
- UP000005640
Subcellular location
- Subcellular Location:
- Membrane
Function
- Function:
- Regulates intra- and extracellular levels of inorganic pyrophosphate (PPi), probably functioning as PPi transporter.
- Gene Ontology Go:
- integral component of membrane
integral component of plasma membrane
outer membrane
plasma membrane
inorganic diphosphate transmembrane transporter activity
inorganic phosphate transmembrane transporter activity
phosphate ion transmembrane transporter activity
inorganic diphosphate transport
locomotory behavior
regulation of bone mineralization
skeletal system development
transmembrane transport - Gene Ontology Biological Process:
- inorganic diphosphate transport
locomotory behavior
regulation of bone mineralization
skeletal system development
transmembrane transport - Gene Ontology Molecular Function:
- inorganic diphosphate transmembrane transporter activity
inorganic phosphate transmembrane transporter activity
phosphate ion transmembrane transporter activity - Gene Ontology Cellular Component:
- integral component of membrane
integral component of plasma membrane
outer membrane
plasma membrane - Keywords:
- Alternative splicing
Complete proteome
Deafness
Disease mutation
Membrane
Phosphate transport
Reference proteome
Transmembrane
Transmembrane helix
Transport