Names & Taxonomy
- Uniprot ID:
- Q9HBW9
- Entry Name:
- AGRL4_HUMAN
- Status:
- reviewed
- Protein Names:
- Adhesion G protein-coupled receptor L4 (EGF, latrophilin and seven transmembrane domain-containing protein 1) (EGF-TM7-latrophilin-related protein) (ETL protein)
- Gene Names:
- ADGRL4 ELTD1 ETL UNQ202/PRO228
- Gene Names Orf:
- UNQ202/PRO228
- Gene Names Primary:
- ADGRL4
- Organism:
- Homo sapiens (Human)
Structure
- Length:
- 690
- Sequence:
- MKRLPLLVVFSTLLNCSYTQNCTKTPCLPNAKCEIRNGIEACYCNMGFSGNGVTICEDDNECGNLTQSCGENANCTNTEGSYYCMCVPGFRSSSNQDRFITNDGTVCIENVNANCHLDNVCIAANINKTLTKIRSIKEPVALLQEVYRNSVTDLSPTDIITYIEILAESSSLLGYKNNTISAKDTLSNSTLTEFVKTVNNFVQRDTFVVWDKLSVNHRRTHLTKLMHTVEQATLRISQSFQKTTEFDTNSTDIALKVFFFDSYNMKHIHPHMNMDGDYINIFPKRKAAYDSNGNVAVAFVYYKSIGPLLSSSDNFLLKPQNYDNSEEEERVISSVISVSMSSNPPTLYELEKITFTLSHRKVTDRYRSLCAFWNYSPDTMNGSWSSEGCELTYSNETHTSCRCNHLTHFAILMSSGPSIGIKDYNILTRITQLGIIISLICLAICIFTFWFFSEIQSTRTTIHKNLCCSLFLAELVFLVGINTNTNKLFCSIIAGLLHYFFLAAFAWMCIEGIHLYLIVVGVIYNKGFLHKNFYIFGYLSPAVVVGFSAALGYRYYGTTKVCWLSTENNFIWSFIGPACLIILVNLLAFGVIIYKVFRHTAGLKPEVSCFENIRSCARGALALLFLLGTTWIFGVLHVVHASVVTAYLFTVSNAFQGMFIFLFLCVLSRKIQEEYYRLFKNVPCCFGCLR
- Proteomes:
- UP000005640
Subcellular location
- Subcellular Location:
- Cell membrane
Function
- Function:
- Endothelial orphan receptor that acts as a key regulator of angiogenesis.
- Gene Ontology Go:
- cytoplasmic vesicle
integral component of membrane
plasma membrane
calcium ion binding
G-protein coupled receptor activity
cell surface receptor signaling pathway
G-protein coupled receptor signaling pathway - Gene Ontology Biological Process:
- cell surface receptor signaling pathway
G-protein coupled receptor signaling pathway - Gene Ontology Molecular Function:
- calcium ion binding
G-protein coupled receptor activity - Gene Ontology Cellular Component:
- cytoplasmic vesicle
integral component of membrane
plasma membrane - Keywords:
- Calcium
Cell membrane
Complete proteome
Disulfide bond
EGF-like domain
G-protein coupled receptor
Glycoprotein
Membrane
Polymorphism
Receptor
Reference proteome
Repeat
Signal
Transducer
Transmembrane
Transmembrane helix