Names & Taxonomy

Uniprot ID:
Q9H2D1
Entry Name:
MFTC_HUMAN
Status:
reviewed
Protein Names:
Mitochondrial folate transporter/carrier (Solute carrier family 25 member 32)
Gene Names:
SLC25A32 MFT MFTC
Gene Names Primary:
SLC25A32
Organism:
Homo sapiens (Human)

Structure

Length:
315
Sequence:
MTGQGQSASGSSAWSTVFRHVRYENLIAGVSGGVLSNLALHPLDLVKIRFAVSDGLELRPKYNGILHCLTTIWKLDGLRGLYQGVTPNIWGAGLSWGLYFFFYNAIKSYKTEGRAERLEATEYLVSAAEAGAMTLCITNPLWVTKTRLMLQYDAVVNSPHRQYKGMFDTLVKIYKYEGVRGLYKGFVPGLFGTSHGALQFMAYELLKLKYNQHINRLPEAQLSTVEYISVAALSKIFAVAATYPYQVVRARLQDQHMFYSGVIDVITKTWRKEGVGGFYKGIAPNLIRVTPACCITFVVYENVSHFLLDLREKRK
Proteomes:
UP000005640

Subcellular location

Subcellular Location:
Mitochondrion inner membrane; Multi-pass membrane protein.

Function

Function:
Transports folate across the inner membranes of mitochondria.
Cross Reference Drug Bank:
DB00158
Gene Ontology Go:
integral component of membrane
mitochondrial inner membrane
mitochondrion
folic acid transporter activity
structural constituent of ribosome
folic acid import into mitochondrion
folic acid metabolic process
folic acid transport
glycine metabolic process
small molecule metabolic process
translation
vitamin metabolic process
water-soluble vitamin metabolic process
Gene Ontology Biological Process:
folic acid import into mitochondrion
folic acid metabolic process
folic acid transport
glycine metabolic process
small molecule metabolic process
translation
vitamin metabolic process
water-soluble vitamin metabolic process
Gene Ontology Molecular Function:
folic acid transporter activity
structural constituent of ribosome
Gene Ontology Cellular Component:
integral component of membrane
mitochondrial inner membrane
mitochondrion
Keywords:
Complete proteome
Membrane
Mitochondrion
Mitochondrion inner membrane
Polymorphism
Reference proteome
Repeat
Transmembrane
Transmembrane helix
Transport

Publication

PubMed ID:
10978331 14702039 15489334 25944712