Names & Taxonomy

Uniprot ID:
Q9BPV8
Entry Name:
P2Y13_HUMAN
Status:
reviewed
Protein Names:
P2Y purinoceptor 13 (P2Y13) (G-protein coupled receptor 86) (G-protein coupled receptor 94)
Gene Names:
P2RY13 GPR86 GPR94 FKSG77
Gene Names Orf:
FKSG77
Gene Names Primary:
P2RY13
Organism:
Homo sapiens (Human)

Structure

Length:
354
Sequence:
MTAAIRRQRELSILPKVTLEAMNTTVMQGFNRSERCPRDTRIVQLVFPALYTVVFLTGILLNTLALWVFVHIPSSSTFIIYLKNTLVADLIMTLMLPFKILSDSHLAPWQLRAFVCRFSSVIFYETMYVGIVLLGLIAFDRFLKIIRPLRNIFLKKPVFAKTVSIFIWFFLFFISLPNTILSNKEATPSSVKKCASLKGPLGLKWHQMVNNICQFIFWTVFILMLVFYVVIAKKVYDSYRKSKSKDRKNNKKLEGKVFVVVAVFFVCFAPFHFARVPYTHSQTNNKTDCRLQNQLFIAKETTLFLAATNICMDPLIYIFLCKKFTEKLPCMQGRKTTASSQENHSSQTDNITLG
Proteomes:
UP000005640

Subcellular location

Subcellular Location:
Cell membrane; Multi-pass membrane protein.

Function

Function:
Receptor for ADP. Coupled to G(i)-proteins. May play a role in hematopoiesis and the immune system.
Gene Ontology Go:
endoplasmic reticulum
integral component of plasma membrane
plasma membrane
G-protein coupled purinergic nucleotide receptor activity
cellular response to organic cyclic compound
negative regulation of adenylate cyclase activity
Gene Ontology Biological Process:
cellular response to organic cyclic compound
negative regulation of adenylate cyclase activity
Gene Ontology Molecular Function:
G-protein coupled purinergic nucleotide receptor activity
Gene Ontology Cellular Component:
endoplasmic reticulum
integral component of plasma membrane
plasma membrane
Keywords:
3D-structure
Alternative splicing
Cell membrane
Complete proteome
Disulfide bond
G-protein coupled receptor
Glycoprotein
Membrane
Polymorphism
Receptor
Reference proteome
Transducer
Transmembrane
Transmembrane helix

Publication

PubMed ID:
11574155 11546776 11273702 12044878 14702039 16641997 15489334