Names & Taxonomy
- Uniprot ID:
- Q99643
- Entry Name:
- C560_HUMAN
- Status:
- reviewed
- Protein Names:
- Succinate dehydrogenase cytochrome b560 subunit, mitochondrial (Integral membrane protein CII-3) (QPs-1) (QPs1) (Succinate dehydrogenase complex subunit C) (Succinate-ubiquinone oxidoreductase cytochrome B large subunit) (CYBL)
- Gene Names:
- SDHC CYB560 SDH3
- Gene Names Primary:
- SDHC
- Organism:
- Homo sapiens (Human)
Structure
- Length:
- 169
- Sequence:
- MAALLLRHVGRHCLRAHFSPQLCIRNAVPLGTTAKEEMERFWNKNIGSNRPLSPHITIYSWSLPMAMSICHRGTGIALSAGVSLFGMSALLLPGNFESYLELVKSLCLGPALIHTAKFALVFPLMYHTWNGIRHLMWDLGKGLKIPQLYQSGVVVLVLTVLSSMGLAAM
- Proteomes:
- UP000005640
Subcellular location
- Subcellular Location:
- Mitochondrion inner membrane; Multi-pass membrane protein.
Function
- Function:
- Membrane-anchoring subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q).
- Pathway:
- Carbohydrate metabolism; tricarboxylic acid cycle.
- Cofactor:
- COFACTOR: Name=heme; Xref=ChEBI:CHEBI:30413;
- Cross Reference Drug Bank:
- DB00139
- Gene Ontology Go:
- integral component of membrane
mitochondrial inner membrane
mitochondrial respiratory chain complex II, succinate dehydrogenase complex (ubiquinone)
mitochondrion
respiratory chain complex II
electron carrier activity
heme binding
metal ion binding
succinate dehydrogenase activity
aerobic respiration
cellular metabolic process
mitochondrial electron transport, succinate to ubiquinone
oxidation-reduction process
respiratory electron transport chain
small molecule metabolic process
tricarboxylic acid cycle - Gene Ontology Biological Process:
- aerobic respiration
cellular metabolic process
mitochondrial electron transport, succinate to ubiquinone
oxidation-reduction process
respiratory electron transport chain
small molecule metabolic process
tricarboxylic acid cycle - Gene Ontology Molecular Function:
- electron carrier activity
heme binding
metal ion binding
succinate dehydrogenase activity - Gene Ontology Cellular Component:
- integral component of membrane
mitochondrial inner membrane
mitochondrial respiratory chain complex II, succinate dehydrogenase complex (ubiquinone)
mitochondrion
respiratory chain complex II - Keywords:
- Alternative splicing
Complete proteome
Electron transport
Heme
Iron
Membrane
Metal-binding
Mitochondrion
Mitochondrion inner membrane
Reference proteome
Transit peptide
Transmembrane
Transmembrane helix
Transport
Tricarboxylic acid cycle