Names & Taxonomy
- Uniprot ID:
- Q96T83
- Entry Name:
- SL9A7_HUMAN
- Status:
- reviewed
- Protein Names:
- Sodium/hydrogen exchanger 7 (Na(+)/H(+) exchanger 7) (NHE-7) (Solute carrier family 9 member 7)
- Gene Names:
- SLC9A7 NHE7
- Gene Names Primary:
- SLC9A7
- Organism:
- Homo sapiens (Human)
Structure
- Length:
- 725
- Sequence:
- MEPGDAARPGSGRATGAPPPRLLLLPLLLGWGLRVAAAASASSSGAAAEDSSAMEELATEKEAEESHRQDSVSLLTFILLLTLTILTIWLFKHRRVRFLHETGLAMIYGLIVGVILRYGTPATSGRDKSLSCTQEDRAFSTLLVNVSGKFFEYTLKGEISPGKINSVEQNDMLRKVTFDPEVFFNILLPPIIFHAGYSLKKRHFFRNLGSILAYAFLGTAVSCFIIGNLMYGVVKLMKIMGQLSDKFYYTDCLFFGAIISATDPVTVLAIFNELHADVDLYALLFGESVLNDAVAIVLSSSIVAYQPAGLNTHAFDAAAFFKSVGIFLGIFSGSFTMGAVTGVNANVTKFTKLHCFPLLETALFFLMSWSTFLLAEACGFTGVVAVLFCGITQAHYTYNNLSVESRSRTKQLFEVLHFLAENFIFSYMGLALFTFQKHVFSPIFIIGAFVAIFLGRAAHIYPLSFFLNLGRRHKIGWNFQHMMMFSGLRGAMAFALAIRDTASYARQMMFTTTLLIVFFTVWIIGGGTTPMLSWLNIRVGVEEPSEEDQNEHHWQYFRVGVDPDQDPPPNNDSFQVLQGDGPDSARGNRTKQESAWIFRLWYSFDHNYLKPILTHSGPPLTTTLPAWCGLLARCLTSPQVYDNQEPLREEDSDFILTEGDLTLTYGDSTVTANGSSSSHTASTSLEGSRRTKSSSEEVLERDLGMGDQKVSSRGTRLVFPLEDNA
- Proteomes:
- UP000005640
Subcellular location
- Subcellular Location:
- Golgi apparatus, trans-Golgi network membrane
Function
- Function:
- Mediates electroneutral exchange of protons for Na(+) and K(+) across endomembranes. May contribute to Golgi volume and cation homeostasis.
- Gene Ontology Go:
- Golgi membrane
integral component of membrane
recycling endosome membrane
trans-Golgi network
potassium:proton antiporter activity
protein homodimerization activity
sodium:proton antiporter activity
ion transport
potassium ion transmembrane transport
regulation of pH
sodium ion transmembrane transport
transmembrane transport - Gene Ontology Biological Process:
- ion transport
potassium ion transmembrane transport
regulation of pH
sodium ion transmembrane transport
transmembrane transport - Gene Ontology Molecular Function:
- potassium:proton antiporter activity
protein homodimerization activity
sodium:proton antiporter activity - Gene Ontology Cellular Component:
- Golgi membrane
integral component of membrane
recycling endosome membrane
trans-Golgi network - Keywords:
- Antiport
Complete proteome
Endosome
Golgi apparatus
Ion transport
Membrane
Phosphoprotein
Potassium
Potassium transport
Reference proteome
Sodium
Sodium transport
Transmembrane
Transmembrane helix
Transport