Names & Taxonomy
- Uniprot ID:
- Q96RH0
- Entry Name:
- Q96RH0_HUMAN
- Status:
- unreviewed
- Protein Names:
- Muscarinic acetylcholine receptor
- Gene Names:
- CHRM2
- Gene Names Primary:
- CHRM2
- Organism:
- Homo sapiens (Human)
Structure
- Length:
- 456
- Sequence:
- MNNSTNSSNNSLALTSPYKTFEVVFIVLVAGSLSLVTIIGNILVMVSIKVNRHLQTVNNYFLFSLACADLIIGVFSMNLYTLYTVIGYWPLGPVVCDLWLALDYVVSNASVMNLLIISFDRYFCVTKPLTYPVKRTTKMAGMMIAAAWVLSFILWAPAILFWQFIVGVRTVEDGECYIQFFSNAAVTFGTAIAAFYLPVIIMTVLYWHISRASKSRIKKDKKEPVANQDPVSPSLVQGRIVKPNNNNMPSSDDGLEHNKIQNGKAPRDPVTENCVQGEEKESSNDSTSVSAVASNMRDDEITQDENTVSTSLGHSKDENSKQTCIRIGTKTPKSDSCTPTNTTVEVVGSSGQNGDEKQNIVARKIVKMTKQPAKKKPPPSREKKVTRTILAILLAFIITWAPYNVMVLINTFCAPCIPNTVWTIGYWLCYINSTINPACYALCNATFKKTFKHLLM
Subcellular location
- Subcellular Location:
- Cell membrane
Function
- Function:
- The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins.
- Gene Ontology Go:
- cell junction
integral component of plasma membrane
postsynaptic membrane
G-protein coupled acetylcholine receptor activity
regulation of heart contraction - Gene Ontology Biological Process:
- regulation of heart contraction
- Gene Ontology Molecular Function:
- G-protein coupled acetylcholine receptor activity
- Gene Ontology Cellular Component:
- cell junction
integral component of plasma membrane
postsynaptic membrane - Keywords:
- Cell junction
Cell membrane
G-protein coupled receptor
Membrane
Postsynaptic cell membrane
Receptor
Synapse
Transducer
Transmembrane
Transmembrane helix