Names & Taxonomy

Uniprot ID:
Q96RG8
Entry Name:
Q96RG8_HUMAN
Status:
unreviewed
Protein Names:
Muscarinic acetylcholine receptor
Gene Names:
CHRM4
Gene Names Primary:
CHRM4
Organism:
Homo sapiens (Human)

Structure

Length:
474
Sequence:
MANFTPVNGSSGNQSVRLVTSSSHNRYETVEMVFIATVTGSLSLVTVVGNILVMLSIKVNRQLQTVNNYFLFSLACADLIIGAFSMNLYTVYIIKGYWPLGAVVCDLWLALDYVVSNASVMNLLIISFDRYFCVTKPLTYPARRTTKMAGLMIAAAWVLSFVLWAPAILFWQFVVGKRTVPDNQCFIQFLSNPAVTFGTAIAAFYLPVVIMTVLYIHISLASRSRVHKHRPEGPKEKKAKTLAFLKSPLMKQSVKKPPPGEAAREELRNGKLEEAPPPALPPPPRPVADKDTSNESSSGSATQNTKERPATELSTTEATTPAMPAPPLQPRALNPASRWSKIQIVTKQTGNECVTAIEIVPATPAGMRPAANVARKFASIARNQVRKKRQMAARERKVTRTIFAILLAFILTWTPYNVMVLVNTFCQSCIPDTVWSIGYWLCYVNSTINPACYALCNATFKKTFRHLLLCQYAR

Subcellular location

Subcellular Location:
Cell membrane

Function

Function:
The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins.
Gene Ontology Go:
cell junction
integral component of plasma membrane
postsynaptic membrane
G-protein coupled acetylcholine receptor activity
regulation of locomotion
Gene Ontology Biological Process:
regulation of locomotion
Gene Ontology Molecular Function:
G-protein coupled acetylcholine receptor activity
Gene Ontology Cellular Component:
cell junction
integral component of plasma membrane
postsynaptic membrane
Keywords:
Cell junction
Cell membrane
G-protein coupled receptor
Membrane
Postsynaptic cell membrane
Receptor
Synapse
Transducer
Transmembrane
Transmembrane helix