Names & Taxonomy
- Uniprot ID:
- Q8TE23
- Entry Name:
- TS1R2_HUMAN
- Status:
- reviewed
- Protein Names:
- Taste receptor type 1 member 2 (G-protein coupled receptor 71) (Sweet taste receptor T1R2)
- Gene Names:
- TAS1R2 GPR71 T1R2 TR2
- Gene Names Primary:
- TAS1R2
- Organism:
- Homo sapiens (Human)
Structure
- Length:
- 839
- Sequence:
- MGPRAKTISSLFFLLWVLAEPAENSDFYLPGDYLLGGLFSLHANMKGIVHLNFLQVPMCKEYEVKVIGYNLMQAMRFAVEEINNDSSLLPGVLLGYEIVDVCYISNNVQPVLYFLAHEDNLLPIQEDYSNYISRVVAVIGPDNSESVMTVANFLSLFLLPQITYSAISDELRDKVRFPALLRTTPSADHHIEAMVQLMLHFRWNWIIVLVSSDTYGRDNGQLLGERVARRDICIAFQETLPTLQPNQNMTSEERQRLVTIVDKLQQSTARVVVVFSPDLTLYHFFNEVLRQNFTGAVWIASESWAIDPVLHNLTELRHLGTFLGITIQSVPIPGFSEFREWGPQAGPPPLSRTSQSYTCNQECDNCLNATLSFNTILRLSGERVVYSVYSAVYAVAHALHSLLGCDKSTCTKRVVYPWQLLEEIWKVNFTLLDHQIFFDPQGDVALHLEIVQWQWDRSQNPFQSVASYYPLQRQLKNIQDISWHTINNTIPMSMCSKRCQSGQKKKPVGIHVCCFECIDCLPGTFLNHTEDEYECQACPNNEWSYQSETSCFKRQLVFLEWHEAPTIAVALLAALGFLSTLAILVIFWRHFQTPIVRSAGGPMCFLMLTLLLVAYMVVPVYVGPPKVSTCLCRQALFPLCFTICISCIAVRSFQIVCAFKMASRFPRAYSYWVRYQGPYVSMAFITVLKMVIVVIGMLATGLSPTTRTDPDDPKITIVSCNPNYRNSLLFNTSLDLLLSVVGFSFAYMGKELPTNYNEAKFITLSMTFYFTSSVSLCTFMSAYSGVLVTIVDLLVTVLNLLAISLGYFGPKCYMILFYPERNTPAYFNSMIQGYTMRRD
- Proteomes:
- UP000005640
Subcellular location
- Subcellular Location:
- Cell membrane; Multi-pass membrane protein.
Function
- Function:
- Putative taste receptor. TAS1R2/TAS1R3 recognizes diverse natural and synthetic sweeteners.
- Cross Reference Drug Bank:
- DB00168
- Gene Ontology Go:
- integral component of membrane
plasma membrane
receptor complex
sweet taste receptor complex
protein heterodimerization activity
taste receptor activity
detection of chemical stimulus involved in sensory perception of sweet taste
G-protein coupled receptor signaling pathway
positive regulation of cytokinesis
sensory perception of sweet taste - Gene Ontology Biological Process:
- detection of chemical stimulus involved in sensory perception of sweet taste
G-protein coupled receptor signaling pathway
positive regulation of cytokinesis
sensory perception of sweet taste - Gene Ontology Molecular Function:
- protein heterodimerization activity
taste receptor activity - Gene Ontology Cellular Component:
- integral component of membrane
plasma membrane
receptor complex
sweet taste receptor complex - Keywords:
- Cell membrane
Complete proteome
G-protein coupled receptor
Glycoprotein
Membrane
Polymorphism
Receptor
Reference proteome
Sensory transduction
Signal
Taste
Transducer
Transmembrane
Transmembrane helix