Names & Taxonomy

Uniprot ID:
Q8TCU3
Entry Name:
S7A13_HUMAN
Status:
reviewed
Protein Names:
Solute carrier family 7 member 13 (Sodium-independent aspartate/glutamate transporter 1) (X-amino acid transporter 2)
Gene Names:
SLC7A13 AGT1 XAT2
Gene Names Primary:
SLC7A13
Organism:
Homo sapiens (Human)

Structure

Length:
470
Sequence:
MDRGEKIQLKRVFGYWWGTSFLLINIIGAGIFVSPKGVLAYSCMNVGVSLCVWAGCAILAMTSTLCSAEISISFPCSGAQYYFLKRYFGSTVAFLNLWTSLFLGSGVVAGQALLLAEYSIQPFFPSCSVPKLPKKCLALAMLWIVGILTSRGVKEVTWLQIASSVLKVSILSFISLTGVVFLIRGKKENVERFQNAFDAELPDISHLIQAIFQGYFAYSGGACFTLIAGELKKPRTTIPKCIFTALPLVTVVYLLVNISYLTVLTPREILSSDAVAITWADRAFPSLAWIMPFAISTSLFSNLLISIFKSSRPIYLASQEGQLPLLFNTLNSHSSPFTAVLLLVTLGSLAIILTSLIDLINYIFFTGSLWSILLMIGILRRRYQEPNLSIPYKVFLSFPLATIVIDVGLVVIPLVKSPNVHYVYVLLLVLSGLLFYIPLIHFKIRLAWFEKMTCYLQLLFNICLPDVSEE
Proteomes:
UP000005640

Subcellular location

Subcellular Location:
Membrane

Function

Function:
Mediates the transport L-aspartate and L-glutamate in a sodium-independent manner.
Gene Ontology Go:
integral component of membrane
antiporter activity
L-amino acid transmembrane transporter activity
neutral amino acid transmembrane transporter activity
L-alpha-amino acid transmembrane transport
L-amino acid transport
neutral amino acid transport
Gene Ontology Biological Process:
L-alpha-amino acid transmembrane transport
L-amino acid transport
neutral amino acid transport
Gene Ontology Molecular Function:
antiporter activity
L-amino acid transmembrane transporter activity
neutral amino acid transmembrane transporter activity
Gene Ontology Cellular Component:
integral component of membrane
Keywords:
Alternative splicing
Amino-acid transport
Complete proteome
Membrane
Polymorphism
Reference proteome
Transmembrane
Transmembrane helix
Transport

Publication

PubMed ID:
11943479 14702039 15489334