Names & Taxonomy
- Uniprot ID:
- Q8TAE7
- Entry Name:
- KCNG3_HUMAN
- Status:
- reviewed
- Protein Names:
- Potassium voltage-gated channel subfamily G member 3 (Voltage-gated potassium channel subunit Kv10.1) (Voltage-gated potassium channel subunit Kv6.3)
- Gene Names:
- KCNG3
- Gene Names Primary:
- KCNG3
- Organism:
- Homo sapiens (Human)
Structure
- Length:
- 436
- Sequence:
- MTFGRSGAASVVLNVGGARYSLSRELLKDFPLRRVSRLHGCRSERDVLEVCDDYDRERNEYFFDRHSEAFGFILLYVRGHGKLRFAPRMCELSFYNEMIYWGLEGAHLEYCCQRRLDDRMSDTYTFYSADEPGVLGRDEARPGGAEAAPSRRWLERMRRTFEEPTSSLAAQILASVSVVFVIVSMVVLCASTLPDWRNAAADNRSLDDRSRYSAGPGREPSGIIEAICIGWFTAECIVRFIVSKNKCEFVKRPLNIIDLLAITPYYISVLMTVFTGENSQLQRAGVTLRVLRMMRIFWVIKLARHFIGLQTLGLTLKRCYREMVMLLVFICVAMAIFSALSQLLEHGLDLETSNKDFTSIPAACWWVIISMTTVGYGDMYPITVPGRILGGVCVVSGIVLLALPITFIYHSFVQCYHELKFRSARYSRSLSTEFLN
- Proteomes:
- UP000005640
Subcellular location
- Subcellular Location:
- Cell membrane
- Intramembrane:
- INTRAMEM 361 372 Helical; Name=Pore helix.
Function
- Function:
- Potassium channel subunit that does not form functional channels by itself (PubMed:11852086). Can form functional heterotetrameric channels with KCNB1; this promotes a reduction in the rate of activation and inactivation of the delayed rectifier voltage-gated potassium channel KCNB1 (PubMed:11852086, PubMed:19074135).
- Gene Ontology Go:
- endoplasmic reticulum
plasma membrane
voltage-gated potassium channel complex
delayed rectifier potassium channel activity
potassium ion transmembrane transport
protein homooligomerization
synaptic transmission - Gene Ontology Biological Process:
- potassium ion transmembrane transport
protein homooligomerization
synaptic transmission - Gene Ontology Molecular Function:
- delayed rectifier potassium channel activity
- Gene Ontology Cellular Component:
- endoplasmic reticulum
plasma membrane
voltage-gated potassium channel complex - Keywords:
- Alternative splicing
Cell membrane
Complete proteome
Cytoplasm
Ion channel
Ion transport
Membrane
Potassium
Potassium channel
Potassium transport
Reference proteome
Transmembrane
Transmembrane helix
Transport
Voltage-gated channel