Names & Taxonomy

Uniprot ID:
Q8NDQ6
Entry Name:
ZN540_HUMAN
Status:
reviewed
Protein Names:
Zinc finger protein 540
Gene Names:
ZNF540 Nbla10512
Gene Names Orf:
Nbla10512
Gene Names Primary:
ZNF540
Organism:
Homo sapiens (Human)

Structure

Length:
660
Sequence:
MAHALVTFRDVAIDFSQKEWECLDTTQRKLYRDVMLENYNNLVSLGYSGSKPDVITLLEQGKEPCVVARDVTGRQCPGLLSRHKTKKLSSEKDIHEISLSKESIIEKSKTLRLKGSIFRNEWQNKSEFEGQQGLKERSISQKKIVSKKMSTDRKRPSFTLNQRIHNSEKSCDSHLVQHGKIDSDVKHDCKECGSTFNNVYQLTLHQKIHTGEKSCKCEKCGKVFSHSYQLTLHQRFHTGEKPYECQECGKTFTLYPQLNRHQKIHTGKKPYMCKKCDKGFFSRLELTQHKRIHTGKKSYECKECGKVFQLIFYFKEHERIHTGKKPYECKECGKAFSVCGQLTRHQKIHTGVKPYECKECGKTFRLSFYLTEHRRTHAGKKPYECKECGKSFNVRGQLNRHKTIHTGIKPFACKVCEKAFSYSGDLRVHSRIHTGEKPYECKECGKAFMLRSVLTEHQRLHTGVKPYECKECGKTFRVRSQISLHKKIHTDVKPYKCVRCGKTFRFGFYLTEHQRIHTGEKPYKCKECGKAFIRRGNLKEHLKIHSGLKPYDCKECGKSFSRRGQFTEHQKIHTGVKPYKCKECGKAFSRSVDLRIHQRIHTGEKPYECKQCGKAFRLNSHLTEHQRIHTGEKPYECKVCRKAFRQYSHLYQHQKTHNVI
Proteomes:
UP000005640

Subcellular location

Subcellular Location:
Nucleus

Function

Function:
May act as a transcriptional repressor.
Gene Ontology Go:
cytoplasm
intracellular membrane-bounded organelle
nucleoplasm
nucleus
DNA binding
metal ion binding
transcription factor activity, sequence-specific DNA binding
translation repressor activity, nucleic acid binding
negative regulation of transcription, DNA-templated
negative regulation of translation
transcription, DNA-templated
Gene Ontology Biological Process:
negative regulation of transcription, DNA-templated
negative regulation of translation
transcription, DNA-templated
Gene Ontology Molecular Function:
DNA binding
metal ion binding
transcription factor activity, sequence-specific DNA binding
translation repressor activity, nucleic acid binding
Gene Ontology Cellular Component:
cytoplasm
intracellular membrane-bounded organelle
nucleoplasm
nucleus
Keywords:
Alternative splicing
Complete proteome
Cytoplasm
DNA-binding
Metal-binding
Nucleus
Polymorphism
Reference proteome
Repeat
Repressor
Transcription
Transcription regulation
Zinc
Zinc-finger

Publication

PubMed ID:
14702039 17974005 15489334 12880961 16815308 16959974 23033978