Names & Taxonomy

Uniprot ID:
Q8N8R3
Entry Name:
MCATL_HUMAN
Status:
reviewed
Protein Names:
Mitochondrial basic amino acids transporter (Carnitine/acylcarnitine translocase-like) (CACT-like) (Mitochondrial carnitine/acylcarnitine carrier protein CACL) (Mitochondrial ornithine transporter 3) (Solute carrier family 25 member 29)
Gene Names:
SLC25A29 C14orf69 ORNT3
Gene Names Primary:
SLC25A29
Organism:
Homo sapiens (Human)

Structure

Length:
303
Sequence:
MALDFLAGCAGGVAGVLVGHPFDTVKVRLQVQSVEKPQYRGTLHCFKSIIKQESVLGLYKGLGSPLMGLTFINALVFGVQGNTLRALGHDSPLNQFLAGAAAGAIQCVICCPMELAKTRLQLQDAGPARTYKGSLDCLAQIYGHEGLRGVNRGMVSTLLRETPSFGVYFLTYDALTRALGCEPGDRLLVPKLLLAGGTSGIVSWLSTYPVDVVKSRLQADGLRGAPRYRGILDCVHQSYRAEGWRVFTRGLASTLLRAFPVNAATFATVTVVLTYARGEEAGPEGEAVPAAPAGPALAQPSSL
Proteomes:
UP000005640

Subcellular location

Subcellular Location:
Mitochondrion inner membrane

Function

Function:
Transports arginine, lysine, homoarginine, methylarginine and, to a much lesser extent, ornithine and histidine. Does not transport carnitine nor acylcarnitines. Functions by both counter-exchange and uniport mechanisms.
Cross Reference Drug Bank:
DB00583
Gene Ontology Go:
integral component of membrane
mitochondrial inner membrane
acyl carnitine transmembrane transporter activity
structural constituent of ribosome
translation
Gene Ontology Biological Process:
translation
Gene Ontology Molecular Function:
acyl carnitine transmembrane transporter activity
structural constituent of ribosome
Gene Ontology Cellular Component:
integral component of membrane
mitochondrial inner membrane
Keywords:
Alternative splicing
Complete proteome
Membrane
Mitochondrion
Mitochondrion inner membrane
Reference proteome
Repeat
Transmembrane
Transmembrane helix
Transport

Publication

PubMed ID:
14702039 12508121 15489334 19287344 24652292 25944712