Names & Taxonomy

Uniprot ID:
Q8IZM9
Entry Name:
S38A6_HUMAN
Status:
reviewed
Protein Names:
Probable sodium-coupled neutral amino acid transporter 6 (N-system amino acid transporter 1) (NAT-1) (Na(+)-coupled neutral amino acid transporter 6) (Solute carrier family 38 member 6)
Gene Names:
SLC38A6 NAT1 SNAT6
Gene Names Primary:
SLC38A6
Organism:
Homo sapiens (Human)

Structure

Length:
456
Sequence:
MEASWGSFNAERGWYVSVQQPEEAEAEELSPLLSNELHRQRSPGVSFGLSVFNLMNAIMGSGILGLAYVLANTGVFGFSFLLLTVALLASYSVHLLLSMCIQTAVTSYEDLGLFAFGLPGKLVVAGTIIIQNIGAMSSYLLIIKTELPAAIAEFLTGDYSRYWYLDGQTLLIIICVGIVFPLALLPKIGFLGYTSSLSFFFMMFFALVVIIKKWSIPCPLTLNYVEKGFQISNVTDDCKPKLFHFSKESAYALPTMAFSFLCHTSILPIYCELQSPSKKRMQNVTNTAIALSFLIYFISALFGYLTFYDKVESELLKGYSKYLSHDVVVMTVKLCILFAVLLTVPLIHFPARKAVTMMFFSNFPFSWIRHFLITLALNIIIVLLAIYVPDIRNVFGVVGASTSTCLIFIFPGLFYLKLSREDFLSWKKLGAFVLLIFGILVGNFSLALIIFDWINK
Proteomes:
UP000005640

Subcellular location

Subcellular Location:
Cell membrane

Function

Function:
Probable sodium-dependent amino acid/proton antiporter, could be a neuronal transporter for glutamate.
Gene Ontology Go:
integral component of plasma membrane
plasma membrane
amino acid transmembrane transporter activity
amino acid transmembrane transport
sodium ion transport
Gene Ontology Biological Process:
amino acid transmembrane transport
sodium ion transport
Gene Ontology Molecular Function:
amino acid transmembrane transporter activity
Gene Ontology Cellular Component:
integral component of plasma membrane
plasma membrane
Keywords:
Acetylation
Alternative splicing
Amino-acid transport
Cell membrane
Complete proteome
Glycoprotein
Ion transport
Membrane
Phosphoprotein
Polymorphism
Reference proteome
Sodium
Sodium transport
Transmembrane
Transmembrane helix
Transport

Publication

PubMed ID:
12508121 15489334 12845534 20068231