Names & Taxonomy
- Uniprot ID:
- Q8IY34
- Entry Name:
- S15A3_HUMAN
- Status:
- reviewed
- Protein Names:
- Solute carrier family 15 member 3 (Osteoclast transporter) (Peptide transporter 3) (Peptide/histidine transporter 2)
- Gene Names:
- SLC15A3 OCTP PHT2 PTR3
- Gene Names Primary:
- SLC15A3
- Organism:
- Homo sapiens (Human)
Structure
- Length:
- 581
- Sequence:
- MPAPRAREQPRVPGERQPLLPRGARGPRRWRRAAGAAVLLVEMLERAAFFGVTANLVLYLNSTNFNWTGEQATRAALVFLGASYLLAPVGGWLADVYLGRYRAVALSLLLYLAASGLLPATAFPDGRSSFCGEMPASPLGPACPSAGCPRSSPSPYCAPVLYAGLLLLGLAASSVRSNLTSFGADQVMDLGRDATRRFFNWFYWSINLGAVLSLLVVAFIQQNISFLLGYSIPVGCVGLAFFIFLFATPVFITKPPMGSQVSSMLKLALQNCCPQLWQRHSARDRQCARVLADERSPQPGASPQEDIANFQVLVKILPVMVTLVPYWMVYFQMQSTYVLQGLHLHIPNIFPANPANISVALRAQGSSYTIPEAWLLLANVVVVLILVPLKDRLIDPLLLRCKLLPSALQKMALGMFFGFTSVIVAGVLEMERLHYIHHNETVSQQIGEVLYNAAPLSIWWQIPQYLLIGISEIFASIPGLEFAYSEAPRSMQGAIMGIFFCLSGVGSLLGSSLVALLSLPGGWLHCPKDFGNINNCRMDLYFFLLAGIQAVTALLFVWIAGRYERASQGPASHSRFSRDRG
- Proteomes:
- UP000005640
Subcellular location
- Subcellular Location:
- Lysosome membrane
Function
- Function:
- Proton oligopeptide cotransporter. Transports free histidine and certain di- and tripeptides (By similarity).
- Gene Ontology Go:
- integral component of membrane
intracellular membrane-bounded organelle
lysosomal membrane
symporter activity
ion transport
peptide transport
protein transport
transmembrane transport - Gene Ontology Biological Process:
- ion transport
peptide transport
protein transport
transmembrane transport - Gene Ontology Molecular Function:
- symporter activity
- Gene Ontology Cellular Component:
- integral component of membrane
intracellular membrane-bounded organelle
lysosomal membrane - Keywords:
- Complete proteome
Glycoprotein
Lysosome
Membrane
Peptide transport
Polymorphism
Protein transport
Reference proteome
Symport
Transmembrane
Transmembrane helix
Transport