Names & Taxonomy
- Uniprot ID:
- Q7Z2K6
- Entry Name:
- ERMP1_HUMAN
- Status:
- reviewed
- Protein Names:
- Endoplasmic reticulum metallopeptidase 1 (EC 3.4.-.-) (Felix-ina)
- Gene Names:
- ERMP1 FXNA KIAA1815
- Gene Names Primary:
- ERMP1
- Organism:
- Homo sapiens (Human)
Structure
- Length:
- 904
- Sequence:
- MEWGSESAAVRRHRVGVERREGAAAAPPPEREARAQEPLVDGCSGGGRTRKRSPGGSGGASRGAGTGLSEVRAALGLALYLIALRTLVQLSLQQLVLRGAAGHRGEFDALQARDYLEHITSIGPRTTGSPENEILTVHYLLEQIKLIEVQSNSLHKISVDVQRPTGSFSIDFLGGFTSYYDNITNVVVKLEPRDGAQHAVLANCHFDSVANSPGASDDAVSCSVMLEVLRVLSTSSEALHHAVIFLFNGAEENVLQASHGFITQHPWASLIRAFINLEAAGVGGKELVFQTGPENPWLVQAYVSAAKHPFASVVAQEVFQSGIIPSDTDFRIYRDFGNIPGIDLAFIENGYIYHTKYDTADRILTDSIQRAGDNILAVLKHLATSDMLAAASKYRHGNMVFFDVLGLFVIAYPSRIGSIINYMVVMGVVLYLGKKFLQPKHKTGNYKKDFLCGLGITLISWFTSLVTVLIIAVFISLIGQSLSWYNHFYVSVCLYGTATVAKIILIHTLAKRFYYMNASAQYLGEVFFDISLFVHCCFLVTLTYQGLCSAFISAVWVAFPLLTKLCVHKDFKQHGAQGKFIAFYLLGMFIPYLYALYLIWAVFEMFTPILGRSGSEIPPDVVLASILAGCTMILSSYFINFIYLAKSTKKTMLTLTLVCAITFLLVCSGTFFPYSSNPANPKPKRVFLQHMTRTFHDLEGNAVKRDSGIWINGFDYTGISHITPHIPEINDSIRAHCEENAPLCGFPWYLPVHFLIRKNWYLPAPEVSPRNPPHFRLISKEQTPWDSIKLTFEATGPSHMSFYVRAHKGSTLSQWSLGNGTPVTSKGGDYFVFYSHGLQASAWQFWIEVQVSEEHPEGMVTVAIAAHYLSGEDKRSPQLDALKEKFPDWTFPSAWVCTYDLFVF
- Proteomes:
- UP000005640
Subcellular location
- Subcellular Location:
- Endoplasmic reticulum membrane
Function
- Function:
- Within the ovary, required for the organization of somatic cells and oocytes into discrete follicular structures.
- Cofactor:
- COFACTOR: Name=Zn(2+); Xref=ChEBI:CHEBI:29105;
- Active Site:
- ACT_SITE 251 251 Proton acceptor.
- Gene Ontology Go:
- endoplasmic reticulum membrane
integral component of membrane
membrane
metal ion binding
metallopeptidase activity - Gene Ontology Molecular Function:
- metal ion binding
metallopeptidase activity - Gene Ontology Cellular Component:
- endoplasmic reticulum membrane
integral component of membrane
membrane - Keywords:
- Acetylation
Alternative splicing
Complete proteome
Disulfide bond
Endoplasmic reticulum
Glycoprotein
Hydrolase
Membrane
Metal-binding
Metalloprotease
Polymorphism
Protease
Reference proteome
Transmembrane
Transmembrane helix
Zinc