Names & Taxonomy
- Uniprot ID:
- Q75V66
- Entry Name:
- ANO5_HUMAN
- Status:
- reviewed
- Protein Names:
- Anoctamin-5 (Gnathodiaphyseal dysplasia 1 protein) (Transmembrane protein 16E)
- Gene Names:
- ANO5 GDD1 TMEM16E
- Gene Names Primary:
- ANO5
- Organism:
- Homo sapiens (Human)
Structure
- Length:
- 913
- Sequence:
- MGDPDLLEVLAEEGEKVNKHIDYSFQMSEQSLSSRETSFLINEETMPAKRFNLFLRRRLMFQKNQQSKDSIFFRDGIRQIDFVLSYVDDVKKDAELKAERRKEFETNLRKTGLELEIEDKRDSEDGRTYFVKIHAPWEVLVTYAEVLGIKMPIKESDIPRPKHTPISYVLGPVRLPLSVKYPHPEYFTAQFSRHRQELFLIEDQATFFPSSSRNRIVYYILSRCPFGIEDGKKRFGIERLLNSNTYSSAYPLHDGQYWKPSEPPNPTNERYTLHQNWARFSYFYKEQPLDLIKNYYGEKIGIYFVFLGFYTEMLFFAAVVGLACFIYGLLSMEHNTSSTEICDPEIGGQMIMCPLCDQVCDYWRLNSTCLASKFSHLFDNESTVFFAIFMGIWVTLFLEFWKQRQARLEYEWDLVDFEEEQQQLQLRPEFEAMCKHRKLNAVTKEMEPYMPLYTRIPWYFLSGATVTLWMSLVVTSMVAVIVYRLSVFATFASFMESDASLKQVKSFLTPQITTSLTGSCLNFIVILILNFFYEKISAWITKMEIPRTYQEYESSLTLKMFLFQFVNFYSSCFYVAFFKGKFVGYPGKYTYLFNEWRSEECDPGGCLIELTTQLTIIMTGKQIFGNIKEAIYPLALNWWRRRKARTNSEKLYSRWEQDHDLESFGPLGLFYEYLETVTQFGFVTLFVASFPLAPLLALINNIVEIRVDAWKLTTQYRRTVASKAHSIGVWQDILYGMAVLSVATNAFIVAFTSDIIPRLVYYYAYSTNATQPMTGYVNNSLSVFLIADFPNHTAPSEKRDFITCRYRDYRYPPDDENKYFHNMQFWHVLAAKMTFIIVMEHVVFLVKFLLAWMIPDVPKDVVERIKREKLMTIKILHDFELNKLKENLGINSNEFAKHVMIEENKAQLAKSTL
- Proteomes:
- UP000005640
Subcellular location
- Subcellular Location:
- Endoplasmic reticulum membrane
Function
- Function:
- Does not exhibit calcium-activated chloride channel (CaCC) activity.
- Gene Ontology Go:
- endoplasmic reticulum membrane
integral component of membrane
intracellular
plasma membrane
vesicle
intracellular calcium activated chloride channel activity
chloride transmembrane transport
chloride transport
ion transmembrane transport
transmembrane transport - Gene Ontology Biological Process:
- chloride transmembrane transport
chloride transport
ion transmembrane transport
transmembrane transport - Gene Ontology Molecular Function:
- intracellular calcium activated chloride channel activity
- Gene Ontology Cellular Component:
- endoplasmic reticulum membrane
integral component of membrane
intracellular
plasma membrane
vesicle - Keywords:
- Cell membrane
Complete proteome
Disease mutation
Endoplasmic reticulum
Glycoprotein
Limb-girdle muscular dystrophy
Membrane
Osteogenesis imperfecta
Polymorphism
Reference proteome
Transmembrane
Transmembrane helix