Names & Taxonomy

Uniprot ID:
Q6U736
Entry Name:
OPN5_HUMAN
Status:
reviewed
Protein Names:
Opsin-5 (G-protein coupled receptor 136) (G-protein coupled receptor PGR12) (Neuropsin) (Transmembrane protein 13)
Gene Names:
OPN5 GPR136 PGR12 TMEM13
Gene Names Primary:
OPN5
Organism:
Homo sapiens (Human)

Structure

Length:
354
Sequence:
MALNHTALPQDERLPHYLRDGDPFASKLSWEADLVAGFYLTIIGILSTFGNGYVLYMSSRRKKKLRPAEIMTINLAVCDLGISVVGKPFTIISCFCHRWVFGWIGCRWYGWAGFFFGCGSLITMTAVSLDRYLKICYLSYGVWLKRKHAYICLAAIWAYASFWTTMPLVGLGDYVPEPFGTSCTLDWWLAQASVGGQVFILNILFFCLLLPTAVIVFSYVKIIAKVKSSSKEVAHFDSRIHSSHVLEMKLTKVAMLICAGFLIAWIPYAVVSVWSAFGRPDSIPIQLSVVPTLLAKSAAMYNPIIYQVIDYKFACCQTGGLKATKKKSLEGFRLHTVTTVRKSSAVLEIHEEWE
Proteomes:
UP000005640

Subcellular location

Subcellular Location:
Membrane; Multi-pass membrane protein.

Function

Gene Ontology Go:
integral component of membrane
11-cis retinal binding
G-protein coupled receptor activity
photoreceptor activity
phototransduction
protein-chromophore linkage
visual perception
Gene Ontology Biological Process:
phototransduction
protein-chromophore linkage
visual perception
Gene Ontology Molecular Function:
11-cis retinal binding
G-protein coupled receptor activity
photoreceptor activity
Gene Ontology Cellular Component:
integral component of membrane
Keywords:
Chromophore
Complete proteome
Disulfide bond
G-protein coupled receptor
Glycoprotein
Lipoprotein
Membrane
Palmitate
Photoreceptor protein
Receptor
Reference proteome
Retinal protein
Sensory transduction
Transducer
Transmembrane
Transmembrane helix

Publication

PubMed ID:
14623103 14623098 12679517 14574404 15489334