Names & Taxonomy

Uniprot ID:
Q6PXP3
Entry Name:
GTR7_HUMAN
Status:
reviewed
Protein Names:
Solute carrier family 2, facilitated glucose transporter member 7 (Glucose transporter type 7) (GLUT-7)
Gene Names:
SLC2A7 GLUT7
Gene Names Primary:
SLC2A7
Organism:
Homo sapiens (Human)

Structure

Length:
512
Sequence:
MENKEAGTPPPIPSREGRLQPTLLLATLSAAFGSAFQYGYNLSVVNTPHKVFKSFYNETYFERHATFMDGKLMLLLWSCTVSMFPLGGLLGSLLVGLLVDSCGRKGTLLINNIFAIIPAILMGVSKVAKAFELIVFSRVVLGVCAGISYSALPMYLGELAPKNLRGMVGTMTEVFVIVGVFLAQIFSLQAILGNPAGWPVLLALTGVPALLQLLTLPFFPESPRYSLIQKGDEATARQALRRLRGHTDMEAELEDMRAEARAERAEGHLSVLHLCALRSLRWQLLSIIVLMAGQQLSGINAINYYADTIYTSAGVEAAHSQYVTVGSGVVNIVMTITSAVLVERLGRRHLLLAGYGICGSACLVLTVVLLFQNRVPELSYLGIICVFAYIAGHSIGPSPVPSVVRTEIFLQSSRRAAFMVDGAVHWLTNFIIGFLFPSIQEAIGAYSFIIFAGICLLTAIYIYVVIPETKGKTFVEINRIFAKRNRVKLPEEKEETIDAGPPTASPAKETSF
Proteomes:
UP000005640

Subcellular location

Subcellular Location:
Membrane; Multi-pass membrane protein.

Function

Function:
High-affinity transporter for glucose and fructose Does not transport galactose, 2-deoxy-d-glucose and xylose.
Gene Ontology Go:
integral component of membrane
plasma membrane
substrate-specific transmembrane transporter activity
carbohydrate transport
transmembrane transport
Gene Ontology Biological Process:
carbohydrate transport
transmembrane transport
Gene Ontology Molecular Function:
substrate-specific transmembrane transporter activity
Gene Ontology Cellular Component:
integral component of membrane
plasma membrane
Keywords:
3D-structure
Complete proteome
Glycoprotein
Membrane
Polymorphism
Reference proteome
Sugar transport
Transmembrane
Transmembrane helix
Transport

Publication

PubMed ID:
15033637 16710414