Names & Taxonomy
- Uniprot ID:
- Q6NUT2
- Entry Name:
- D19L2_HUMAN
- Status:
- reviewed
- Protein Names:
- Probable C-mannosyltransferase DPY19L2 (EC 2.4.1.-) (Dpy-19-like protein 2) (Protein dpy-19 homolog 2)
- Gene Names:
- DPY19L2 UNQ3127/PRO10284
- Gene Names Orf:
- UNQ3127/PRO10284
- Gene Names Primary:
- DPY19L2
- Organism:
- Homo sapiens (Human)
Structure
- Length:
- 758
- Sequence:
- MRKQGVSSKRLQSSGRSQSKGRRGASLAREPEVEEEMEKSALGGGKLPRGSWRSSPGRIQSLKERKGLELEVVAKTFLLGPFQFVRNSLAQLREKVQELQARRFSSRTTLGIAVFVAILHWLHLVTLFENDRHFSHLSSLEREMTFRTEMGLYYSYFKTIIEAPSFLEGLWMIMNDRLTEYPLIINAIKRFHLYPEVIIASWYCTFMGIMNLFGLETKTCWNVTRIEPLNEVQSCEGLGDPACFYVGVIFILNGLMMGLFFMYGAYLSGTQLGGLITVLCFFFNHGEATRVMWTPPLRESFSYPFLVLQMCILTLILRTSSNDRRPFIALCLSNVAFMLPWQFAQFILFTQIASLFPMYVVGYIEPSKFQKIIYMNMISVTLSFILMFGNSMYLSSYYSSSLLMTWAIILKRNEIQKLGVSKLNFWLIQGSAWWCGTIILKFLTSKILGVSDHIRLSDLIAARILRYTDFDTLIYTCAPEFDFMEKATPLRYTKTLLLPVVMVITCFIFKKTVRDISYVLATNIYLRKQLLEHSELAFHTLQLLVFTALAILIMRLKMFLTPHMCVMASLICSRQLFGWLFRRVRFEKVIFGILTVMSIQGYANLRNQWSIIGEFNNLPQEELLQWIKYSTTSDAVFAGAMPTMASIKLSTLHPIVNHPHYEDADLRARTKIVYSTYSRKSAKEVRDKLLELHVNYYVLEEAWCVVRTKPGCSMLEIWDVEDPSNAANPPLCSVLLEDARPYFTTVFQNSVYRVLKVN
- Proteomes:
- UP000005640
Subcellular location
- Subcellular Location:
- Membrane
Function
- Function:
- Probable C-mannosyltransferase that mediates C-mannosylation of tryptophan residues on target proteins (By similarity). Required during spermatogenesis for sperm head elongation and acrosome formation.
- Gene Ontology Go:
- integral component of membrane
nuclear inner membrane
nucleus
mannosyltransferase activity
multicellular organism development
protein C-linked glycosylation via 2'-alpha-mannosyl-L-tryptophan
spermatid development - Gene Ontology Biological Process:
- multicellular organism development
protein C-linked glycosylation via 2'-alpha-mannosyl-L-tryptophan
spermatid development - Gene Ontology Molecular Function:
- mannosyltransferase activity
- Gene Ontology Cellular Component:
- integral component of membrane
nuclear inner membrane
nucleus - Keywords:
- Alternative splicing
Complete proteome
Developmental protein
Differentiation
Glycosyltransferase
Membrane
Polymorphism
Reference proteome
Spermatogenesis
Transferase
Transmembrane
Transmembrane helix