Names & Taxonomy

Uniprot ID:
Q5TF39
Entry Name:
MFS4B_HUMAN
Status:
reviewed
Protein Names:
Sodium-dependent glucose transporter 1 (Major facilitator superfamily domain-containing protein 4B)
Gene Names:
MFSD4B KIAA1919 NAGLT1 HSPC100
Gene Names Orf:
HSPC100
Gene Names Primary:
MFSD4B
Organism:
Homo sapiens (Human)

Structure

Length:
518
Sequence:
MLCASFLGLGLSVAIVGPTFQDLATNVNRNISSLSFIFVGRALGYLSGSVIGGFLVDVMNYFLLLGISMSATTVGLYLVPFCKTAILLTVMMSIFGVSIGILDTGGNVLILAIWGDKGAPHMQALHFSFALGAFLAPLLAKLALGPTASAENHTESDFHPALNQSSDADSEALFGVPNDKNLLWAYAVIGTYMFLVSVIFFCLFLKNSSKQEKARASAETFRRAKYHNALLCLLFLFFFFYVGAEVTYGSYVFSFATTHAGMKESEAAGLNSIFWGTFAACRGLAIFFATCLQPGTMIVLSNIGSLTSSLFLVLFDKNPICLWIATSVYGASMATTFPSGVSWIEQYTTIHGKSAAFFVIGASLGEMAIPAVIGILQGKYPDLPVVLYTSLGASIATGILFPVLYKLATSPLDRQRKEDRKSEDQKALLSSSGLNEYEEENEEEDAEKWNEMDFEMIETNDTMRHSIIETSRSSLTEPTAEVYNQYPSNALVFESSPFNTGSAHVKHLPETRTKGTNV
Proteomes:
UP000005640

Subcellular location

Subcellular Location:
Apical cell membrane

Function

Function:
May function as a sodium-dependent glucose transporter. Potential channels for urea in the inner medulla of kidney.
Gene Ontology Go:
apical plasma membrane
integral component of membrane
symporter activity
carbohydrate transport
sodium ion transport
Gene Ontology Biological Process:
carbohydrate transport
sodium ion transport
Gene Ontology Molecular Function:
symporter activity
Gene Ontology Cellular Component:
apical plasma membrane
integral component of membrane
Keywords:
Cell membrane
Complete proteome
Ion transport
Membrane
Polymorphism
Reference proteome
Sodium
Sodium transport
Sugar transport
Symport
Transmembrane
Transmembrane helix
Transport

Publication

PubMed ID:
14702039 14574404 15489334 11572484